Tag Archives: regulation

Researchers identify key molecule which halts transcription of cell’s genetic code.

Elongin A (green) and CUL5 (red) in cells enrich at sites of localized DNA damage.  Credit:  Conaway Lab, Stowers Institute for Medical Research.

When cells are normal and unstressed, the molecule keeps transcription moving so that genes are ‘expressed’ and RNA is jotted down more quickly. When cells are stressed and transcription runs into a glitch caused by damage to the DNA, it marks the machinery to be disassembled. Now, researchers at the Stowers Institute for Medical Research have shown that a molecule

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