New work by scientists from the Children’s Hospital of Philadelphia details how subtle changes in mitochondrial function may cause a broad range of common metabolic and degenerative diseases. Mitochondria are tiny energy-producing structures within human cells that contain their own DNA. The new research shows that small changes in the ratio of mutant to normal mitochondrial DNA within the thousands of mitochondrial DNAs inside each … Continue reading Steadily rising increases in mitochondrial DNA mutations cause abrupt shifts in disease.