Glioblastomas are a highly aggressive type of brain tumour, with few effective treatment options. Moffitt Cancer Center researchers are one step closer to understanding glioblastoma development following the identification of … Continue Reading Researchers map protein pathway involved in brain tumour stem cell growth.
Researchers from the NYU Langone Medical Center and New York University have demonstrated that a specialized DNA-binding protein called CTCF is essential for the precise expression of genes that control … Continue Reading Researchers identify specialized protein crucial for normal neurodevelopment.
A three-character code brings relief to patients with psoriasis and sheds light on complex immunoregulation processes, IL-4, an abbreviation for the endogenous signaling molecule Interleukin 4. The substance’s ability to … Continue Reading Researchers harness the body’s own immune system to counteract psoriasis.
Neuroscientists believe that the connectome, a map of each and every connection between the millions of neurons in the brain, will provide a blueprint that will allow them to link … Continue Reading Researchers identify gated-intermediary neuron system which acts as synaptic cloaking device.
New imaging technique successfully detects Peripheral Arterial Disease in diabetic patients in study.
Approximately 8 to 12 million people in the United States alone are suffering from peripheral arterial disease (PAD), a common vascular problem that is caused by narrowing of the arteries … Continue Reading New imaging technique successfully detects Peripheral Arterial Disease in diabetic patients in study.
A unique class of proteins in the human body has the ability to alter their configuration. These so-named intrinsically disordered proteins (IDPs) lack a fixed or ordered three-dimensional structure, which … Continue Reading Researchers investigate how form affects function and aggregation of tau protein in the brain.
A team led by UC San Francisco has discovered why mucus in the lungs of people with cystic fibrosis (CF) is thick, sticky and difficult to cough up, leaving these … Continue Reading Researchers identify the mechanism cystic fibrosis uses to thicken mucus in the lungs.
Researchers identify gene mutation that raises risk of nerve damage in leukemia patients using Vincristine.
Researchers from St. Jude Children’s Research Hospital have identified the first genetic variation that is associated with increased risk and severity of peripheral neuropathy following treatment with a widely used … Continue Reading Researchers identify gene mutation that raises risk of nerve damage in leukemia patients using Vincristine.
The signal molecule, retinoic acid, is a product of vitamin A which helps to instruct how different types of tissue are to be formed in the growing embryo. For the … Continue Reading Previously unknown effect of vitamin A on embryonic development identified.
Working with cells taken from children with a very rare but aggressive form of brain cancer, Johns Hopkins University scientists have identified a genetic pathway that acts as a master … Continue Reading Researchers map epigenetic pathway as target for therapy of aggressive pediatric brain cancer.
Mutation of one gene is all it takes to get cystic fibrosis (CF), but disease severity depends on many other genes and proteins. For the first time, researchers at the … Continue Reading Researchers map epigenetic pathways linked to cystic fibrosis disease severity.
Researchers at the Medical College of Wisconsin (MCW) have linked a specific protein to the development of post-viral infection asthma, which is the first step in generating a novel type … Continue Reading Researchers identify protein responsible for post-viral asthma in young children.
The Centers for Disease Control and Prevention (CDC) is reporting on the discovery of a new virus that may have contributed to the death of a previously healthy man in … Continue Reading The CDC announces the discovery of a new virus.
Chronic wasting disease (CWD), an infectious disease caused by prions, affects North American elk and deer, but has not been observed in humans. Using a mouse model that expresses an … Continue Reading Small loop in human prion protein shown to prevent chronic wasting disease.
The average heart beats 35 million times a year, 2.5 billion times over a lifetime. Those beats must be precisely calibrated; even a small divergence from the metronomic rhythm can … Continue Reading Researchers identify protein responsible for keeping the heart beating on time.
Tumours require blood to emerge and spread. That is why scientists at The University of Texas MD Anderson Cancer Center believe that targeting blood vessel cells known as pericytes may … Continue Reading Breast cancer metastasis slowed by targeting cells that regulate blood flow.