Myocardial infarction, commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. ST-elevation myocardial infarctions are the … Continue Reading Study shows cold weather can cause, predict higher risk of severe heart attack.
Most mammalian tissues contain autonomous circadian clocks that are synchronized by the suprachiasmatic nuclei (SCN) in the brain. The SCN clock itself is entrained by external light cycles through retinal … Continue Reading Researchers identify how the mammalian retina bypasses the body’s circadian clock.
Neural stem cells generate new neurons throughout life in the mammalian brain. Neural stem cells are self-renewing, multipotent cells that generate the main phenotype of the nervous system. Stem cells … Continue Reading Researchers identify neuroprotective mechanism against stem cell aging.
Antigen receptor genes are assembled by controlled, large-scale deletions and inversions. Errors in this process, known as V(D)J recombination, produce aberrant genomic rearrangements, which can fuel the development of T- … Continue Reading Researchers identify points where incorrect immune cell DNA editing causes blood cancer.
Alzheimer’s is the most common form of dementia globally and affects up to 40,000 people in Ireland today. It is the fourth leading cause of death in individuals over the … Continue Reading Researchers have discovered clearance of Alzheimer’s protein across the blood-brain barrier.
DNA methylation is essential for the proper control of gene expression and cell identity, what enables cells with the same genetic material to become, for example, a nerve cell, a … Continue Reading Single-cell imaging developed which can record DNA methylation in real time.
White adipose tissue, or fat tissue, serves as a storage depot for energy-rich triglycerides. In times of need this lipid storage can be released as part of an adaptive response … Continue Reading Researchers identify previously unknown neural mechanism responsible for fat breakdown.
It has long been known that there is a linear connection between sperm motility and chances of becoming pregnant. Sperm motility describes the ability of sperm to move properly through … Continue Reading Study finds lower sperm motility in men exposed to a common, everyday chemical.
Mobility after paraplegia due to spinal cord injury (SCI) is primarily achieved by substituting the lost function with a wheelchair. However, the sedentary lifestyle associated with excessive wheelchair reliance can … Continue Reading Brain-computer interface enables paralyzed man to walk in world’s first.
Human multitasking is the apparent performance by an individual of handling more than one task, or activity, at the same time. Studies have shown that some people can be trained … Continue Reading Neuroimaging study maps the neural basis of multitasking.
Statins are a popular and easy-to-swallow option for people looking to lower their cholesterol. However, for a quarter of patients, statins come with muscle pain, stiffness, cramps, or weakness without … Continue Reading Researchers link statins to disruption of muscle mitochondria.
Morphine mediates its euphoric and analgesic effects by acting on the μ-opioid receptor (MOR). MOR belongs to the family of G-protein coupled receptors whose signaling efficiency is controlled by the … Continue Reading Researchers identify key morphine regulator in the brain.
Ten million Canadians are living with diabetes or pre-diabetes. The Canadian Diabetes Association reports that more than 20 Canadians are newly diagnosed with the disease every hour of every day. … Continue Reading New mitochondria-based insulin amplifier pathway identified in T2 diabetes.
Methylation is a process where a methyl group is added into critical points along human DNA. In cancer, many regions of the DNA are not methylated, leading to untimely gene … Continue Reading Researchers identify an epigenetic mechanism for colon cancer proliferation.
Humans are unique among social creatures in their willingness to bear personal costs to punish those who have harmed others. Despite the centrality of such third-party punishment decisions to modern … Continue Reading Neuroimaging identifies uniquely human brain region responsible for judgment.
Sickle cell disease is inherited. It primarily affects people of African descent, including about one in every 500 African Americans born in the U.S. The defect causes the oxygen-carrying red … Continue Reading Researchers validate non-chemotherapy based cure for sickle cell in adults.