Many patients with bipolar disorder, a debilitating mental condition that can take a person from the sluggishness of severe depression to super-human energy levels, are often misdiagnosed as having major … Continue Reading Medicalising, differentiating between major depressive and bipolar disorder.
Low levels of serotonin in the brain are known to play a role in depression and anxiety, the involvement of serotonin (5-HT) in regulating emotional behaviour is firmly established. In … Continue Reading Researchers uncover new serotonin neuronal mechanism in depression.
During embryonic development, billions of neurons nimbly reposition themselves within the brain and spinal cord, and connect branches to form the neural circuits that ultimately control our movements, perception, and … Continue Reading Previously unknown molecule critical for neurodevelopment identified.
Malaria is one of the world’s leading health problems. More than 40 percent of the world’s population live in areas where there is a risk of contracting the disease. According … Continue Reading Researchers successfully genetically-engineer mosquitoes which can’t carry malaria.
ALL is identified in about 3,000 individuals each year aged 19 or younger in the U.S., making it the most common childhood cancer. While the cause remains largely unknown, only … Continue Reading Researchers identify inherited gene variation linked to greater acute lymphoblastic leukemia risk.
Cocaine is a strong central nervous system stimulant that increases levels of the neurotransmitter dopamine in brain circuits regulating pleasure and movement. Normally, dopamine is released by neurons in these … Continue Reading Researchers begin to map brain regions and circuits changed by cocaine-use.
In comparison to other organs, the human brain has the highest energy requirements. The supply of energy for nerve cells and the particular role of lactic acid (lactate) has been … Continue Reading Study confirms 20 year-old hypothesis on the brain using lactate for energy.
People with diabetes are more likely to have high blood pressure and high cholesterol and are much more likely to develop cholesterol blockages in their arteries. A person with diabetes … Continue Reading 3-D MRI can show stroke risk in diabetic patients even before narrowing of arteries.
Huntington’s disease is an inherited disorder that damages nerve cells and causes parts of the brain to deteriorate, leading to uncontrolled movements and cognitive problems. There is no way to … Continue Reading Study identifies previously unknown proteins in Huntington’s disease pathology.
Expanded use of engineered nanoparticles in consumer products and drug delivery increases the potential for environmental release, overexposure or unintended biological exposure. As a result, extraction techniques with integrated measurement … Continue Reading New technique can remove nanoparticles unaltered from blood with ease.
Obesity is a significant risk factor for cardiovascular disease, diabetes, and cancer. Although obesity can stem from behavioural factors such as diet and physical inactivity, central nervous system changes can … Continue Reading Neuroimaging maps areas of the brain in obese children activated by food odours.
Irreversible degeneration of the cardiac conduction system is a common disease with high rates of mortality. While electronic pacemakers provide effective treatment, alternative approaches are needed with long-term implanted hardware … Continue Reading Extensive lit review performed on harnessing stem cells to generate biological pacemakers.
Ghrelin is a peptide released from the empty stomach into circulation, and which acts on the brain to promote appetite. Recent studies showed that ghrelin also affects learning and memory, … Continue Reading Study identifies previously unknown mechanism of memory formation in the brain.
In the field of iPS cell-based regenerative medicine, advanced research with clinical applications for many organs and tissues, such as the retina, has steadily progressed. However, growing a kidney from … Continue Reading Human stem cell-derived kidneys connect to blood vessels when transplanted into mice.
Chronic total occlusion, the complete blockage of the coronary artery, represents a major challenge for cardiologists globally. The situation is driven by the unpredictable surgical success rates related to the … Continue Reading World’s first as virtual reality used to guide human coronary procedure.
While some things may be ‘as simple as black and white,’ this has not been the case for the circuits in the brain that make it possible for a person … Continue Reading Study visualises, maps cortical circuits that encode black and white for the first time.