Researchers learn how to grow old brain cells – neuroinnovations
Direct Conversion of Young and Old Human Fibroblasts into Functional iNs Is Efficient Regardless of Donor Age. Immunocytochemical characterization of iN from young and old donors after 3 weeks of conversion. All of the scale bars represent 20 mM. Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects. Gage et al 2015.