Viral infections leave a signature – healthinnovations

Network analysis of the 127-gene Influenza signature using Ingenuity Pathway Analysis. Of the 127 identified genes, 71 are involved in innate virus sensing and initiation of antiviral response pathways. Yellow boxes indicate transcription factors (STAT1, IRF7), RIG-1-like receptors (RLRs), 2’-5’-oligoadenylate synthetases and Interferon-induced proteins that have been previously implicated in response to influenza infection. Integrated, Multi-cohort Analysis Identifies Conserved Transcriptional Signatures across Multiple Respiratory Viruses. Khatri et al 2015.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.