It is known that Parkinson’s disease, the second most common neurodegenerative disease, has genetic causes in 15% of cases. It has been shown that premature aging of dopaminergic neurons in the … Continue Reading Study shows how defective gene prematurely ages neurons in Parkinson’s disease.
The innate immune system is hard-wired to protect people from infection. However, mutations in these protective genes can lead to uncontrolled inflammation, resulting in autoinflammatory disease. Autoinflammatory diseases are characterized … Continue Reading Precision medicine study identifies decades-old mysterious, rare and debilitating disease.
After suffering a stroke, which is estimated to kill more than 6 million people annually, about three-quarters of patients exhibit some disability. It is known that most strokes occur when … Continue Reading Novel neuroprotector successfully reduces brain damage after stroke in preclinical studies.
Being able to detect early on whether a cancer therapy is working proffers obvious benefits for therapy-outcomes whilst influencing the course of treatment and improving the quality of life for … Continue Reading Novel ‘reporter’ nanoparticle reveals cancer treatment effectiveness in real-time.
It is known that Amyotrophic Lateral Sclerosis (ALS) gradually kills nerve cells in the brain and spinal cord. It is one of the most prevalent neuromuscular diseases, resulting in more … Continue Reading Study shows microglia has a direct role in the development of Lou Gehrig’s disease.
Pancreatic cancer is a devastating disease, with a death rate close to the incidence rate. Because more than 90% of pancreatic cancer cases are diagnosed at the metastatic stage, when … Continue Reading Early indicators of pancreatic cancer identified in precision medicine study.
Mitochondria are spherical or rod-shaped organelles found within the cytoplasm of eukaryotic cells, referred to as the powerhouse of the cell as they act as the site for the production … Continue Reading Decades-long mystery solved of how mitochondria’s energy currency is maintained.
Neuropathic pain is deﬁned as pain initiated or caused by a primary lesion or dysfunction in the nervous system. Chronic neuropathic leg pain is the most common form of neuropathic … Continue Reading Neuroimaging shows that spinal cord stimulation reduces emotional aspect of chronic pain.
It is known that natural killer cells, a type of white blood cell prevalent in the body, deliver lethal toxic granules into cells that have become cancerous or infected, causing … Continue Reading Identification of master regulator for specialised immune cell raises hope in cancer fight.
The autonomic nervous system, made up of sympathetic and parasympathetic branches, is known to regulate blood glucose levels by directly controlling insulin secretion by the pancreas. Insulin secretion and blood … Continue Reading Hormone inhibits neuronal connections between the brain and pancreas in neurodevelopment.
The human genome is composed of 20,000 genes and as of today, 3,200 of these genes are known to cause diseases, of which 1,700 are associated with ‘recessive’ diseases. Recessive … Continue Reading Researchers identify a previously unknown neurogenetic recessive disease.
Unprecedented precision study identifies the four genes responsible for blood stem cell development.
Every day, over 100 billion new mature blood cells are generated in an adult human. This major production places high demands on the blood stem cells which must be capable … Continue Reading Unprecedented precision study identifies the four genes responsible for blood stem cell development.
All animals need to sleep for varying durations and in humans, sleep duration changes over their lifetime, gradually reducing from birth through to old age. The mammalian body appears to … Continue Reading Researchers identify neurogenetics responsible for sleep duration.
In a cancerous breast, researchers have seen the problems with the various components of breast tissue and could not fully explain why they happened. The tissue, called the stroma, includes … Continue Reading Human study identifies new gene as cause and early indicator of breast cancer.
Macrophages, also known as scavenger cells, are immune cells which are part of the innate immune system and differentiate from monocytes. They circulate in the bloodstream and upon differentiation, invade … Continue Reading New study refutes textbook theory on macrophage metabolism.
The human brain has a prodigious demand for energy, it uses 20 to 30% of the body’s energy budget. In the course of normal aging, in people with neurodegenerative diseases … Continue Reading Researchers use dietary supplement to re-energize aging brains in animal model.