The innate immune system is hard-wired to protect people from infection. However, mutations in these protective genes can lead to uncontrolled inflammation, resulting in autoinflammatory disease.  Autoinflammatory diseases are characterized by recurrent episodes of fever with systemic and organ-specific inflammation, as well as uncontrolled activation of the innate immune response in the apparent absence of an infectious trigger.  Now, a mysterious, decades-old autoinflammatory disease has … Continue reading Precision medicine study identifies decades-old mysterious, rare and debilitating disease.