There has been much focus on how to prevent heart disease by regulating the secretion of very low density lipoproteins (VLDL) by the liver. These lipoproteins are known to increase … Continue Reading Study shows damage to previously unknown liver protein leads to heart disease, fatty liver.
Approximately 16% of adults in the United States report drug use, however, not everyone who experiments with drugs becomes an addict. Environmental and societal factors play a role in addiction … Continue Reading First ever study identifies epigenetic markers that influence addiction in animal model.
Multiple myeloma, also known as myeloma, is a type of bone marrow cancer. Multiple myeloma affects the plasma cells, blood cell, inside the bone marrow. Myeloma does not take the form of a … Continue Reading Study is first to link multiple myeloma protein to extramedullary disease.
In oncology, the Warburg effect is the observation that that the driver of tumourigenesis is an insufficient cellular respiration caused by insult to mitochondria. It postulates that most cancer cells, … Continue Reading Study uncovers vital Warburg effect pathway in brain tumour formation and metabolism.
Acute HIV-1 infection is the phase of HIV-1 disease immediately after infection that is characterized by an initial burst of viremia; although anti-HIV-1 antibodies are undetectable, HIV-1 RNA or p24 … Continue Reading Study captures HIV study early to successfully characterise the elusive acute infection period.
Nervous system injuries affect over 90,000 people every year, with spinal cord injuries alone estimated to affect 10,000 people each year. As a result of this high incidence of neurological … Continue Reading Researchers successfully control mitochondria to regenerate damaged neurons.
Telomere dysfunction has been proposed as a key event that causes cancer progression. According to this model, progressive telomere shortening results in telomere dysfunction and end-to-end chromosomal fusions. The resulting … Continue Reading Researchers identify telomere-based mechanism which turns mutant cells into aggressive cancers.
Autism spectrum disorder (ASD) is a neurodevelopmental condition that manifests in early childhood and is characterized by impairments in social communication and presence of stereotyped behaviours and restricted interests, with … Continue Reading Mothers with diabetes more likely to have autism-linked anti-fetal brain autoantibodies.
Heart failure is one of the main health problems worldwide, and the urgent medical needs relating to it have positioned cardiovascular research as one of the most actively evolving fields … Continue Reading Study links adult heart regeneration to telomere length in animal model.
A strand of DNA is a very long, narrow string, just a few nanometers across. Single-molecule orientation measurements provide unparalleled insight into a multitude of biological and polymeric systems. Single-molecule … Continue Reading New imaging technique reveals unprecedented nanoscale details about DNA.
Delayed deterioration of neurological function after ischemia stroke is a well-documented clinical problem. However, minimal studies exist pertaining to spinal cord blood flow and blood-spinal cord barrier (BSCB) integrity with … Continue Reading Study maps how a stroke damages the blood-spinal cord barrier.
With the growing prevalence of childhood obesity, the incidence of type 2 diabetes in children and adolescents is increasing at an alarming rate. Type 2 diabetes may become the most … Continue Reading Neuroimaging shows gray matter changes in brains of teenagers with type 2 diabetes.
When the body is fighting an invading pathogen, white blood cells, including T cells, must respond. T-cell receptors (TCRs) recognize pathogens during T-cell–mediated adaptive immune responses. The binding between TCRs … Continue Reading New imaging provides unprecedented detail of immune cells’ surface.
Smoking and alcohol drinking are major causes of oesophageal cancer, particularly in many high-income countries. However, the majority of oesophageal cancers occur in parts of Asia, South America, and East … Continue Reading Piping hot drinks shown by WHO to increase risk of oesophageal cancer.
It is known that one of the earliest sites of Alzheimer’s disease pathology is the hippocampus, a brain structure critical for the learning and memory processes that falter early in Alzheimer’s … Continue Reading Study shows how Alzheimer’s risk gene disrupts memory replay.
More than 600,000 patients in the United States alone suffer from end-stage liver disease, or cirrhosis. The only available cure is liver transplantation, but the shortage of donor livers means … Continue Reading New approach repairs living liver from within with no need of cell transplants.