As they go about their everyday lives, people often have to choose between a safe option and a riskier one, such as staying in a secure job, or starting a … Continue Reading Study identifies neural circuits involved in making risky decisions.
It is known that the formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. The large-scale appearance of … Continue Reading Previously unknown gene mutation in hereditary colon cancer identified.
Stem cells are non-specialized cells found in different organs, which have the capacity to generate specialized cells in the body. In the adult brain, neural stem cells give rise to … Continue Reading Study shows cerebrospinal fluid signals control the behaviour of stem cells in the brain.
The pandemic of physical inactivity is associated with a range of chronic diseases and early deaths. Despite the well documented disease burden, the economic burden of physical inactivity remains unquantified … Continue Reading Physical inactivity cost the world $67 billion in 2013 says first ever estimate.
One of the processes associated with aging is progressive shortening of telomeres, DNA-protecting structures at the ends of chromosomes, like the plastic tips on shoelaces. Each time a cell divides, … Continue Reading Male hormone reverses cell aging, increases telomere length, in clinical trial.
Understanding the integrative role of the central nervous system in the prevalence of obesity and obesity-related diseases is of great importance. It has been hypothesized that flexibility of food reward–related … Continue Reading Neuroimaging shows that response to food cues differ in severely obese women.
Prematurely born babies may experience lifelong, debilitating consequences with the underlying mechanisms of this condition not well understood, due in part to the difficulties of experimenting with intact, living human … Continue Reading Researchers successfully develop first ever placenta-on-a-chip.
Alzheimer’s disease (AD) is common and highly heritable with many gene variants associated with it. However, the genetic risk for AD have not been clearly delineated, with the stage of … Continue Reading Study identifies a genetic risk score for Alzheimer’s disease in young adults.
One of the world’s most deadly diseases, tuberculosis, primarily a lung disease, infects more than 8 million people and is responsible for 1.5 million deaths each year. According to the … Continue Reading Previously unknown method of tuberculosis infection identified.
In alcoholism and addictive drugs repeated exposure triggers glutamatergic and GABAergic plasticity in many neuronal populations. The dorsomedial striatum (DMS), a brain region critically involved in addiction, contains medium spiny … Continue Reading Researchers identify and successfully activate neurons that tell the brain to stop drinking.
The WHO recommends complete withdrawal of the oral polio vaccine (OPV) by April 2016 globally and replacing with at least one dose of inactivated poliovirus vaccine (IPV). However, high-cost, limited … Continue Reading Researchers develop plant-based Polio booster vaccine.
The control of breathing is essential for life. Without an adequate response to increased carbon dioxide levels, people can suffer from breathing disturbances, sickness, and panic; in worst-case scenarios, it … Continue Reading Novel brainstem model show how the brain controls breathing.
Colorectal cancer is the development of cancer from the colon or rectum, due to the abnormal growth of cells that have the ability to invade or spread to other parts … Continue Reading Genetic cause of 15% of all colorectal cancer diagnoses identified.
Leukemia, or blood cancer, involves pathological alterations in the body’s hematopoietic system. In acute myeloid leukemia, it is specifically the bone marrow that is affected. In a healthy body, different … Continue Reading Previously unknown cell-death pathway mapped in leukemia cells.
Charcot-Marie-Tooth Disease (CMT) is a family of inherited disorders of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most … Continue Reading Researchers identify previously unknown genetic cause of inherited neuropathy.
In Kennedy’s disease, the muscle cells and motor neurons, which are also linked to muscle function, are damaged as a result of the accumulation of androgen receptor fibers, a process … Continue Reading Identification of a neuroprotector linked to a degenerative neuromuscular disease.