Genetic variation accounts for a major proportion of the liability to autism spectrum disorder (ASD). Now, a study from led by researchers at UCLA shows that in families with multiple … Continue Reading Largest study of its kind sheds new light on the complex genetics of autism.
Alzheimer’s disease is characterized by the degeneration of neurons in the hippocampus and cortex, and the appearance of neuritic plaques and neurofibrillary tangles. Although the precise cause of Alzheimer’s disease remains … Continue Reading Researchers elevate brain protein to allay symptoms of Alzheimer’s in animal model.
Epilepsy is a common neurological condition characterized by spontaneous, recurrent synchronous discharges of a population of neurons, unprovoked by a known proximal cause. Epilepsy is the second most common neurological … Continue Reading Relief for epilepsy at the scale of a single cell.
According to the World Health Organization, cancer is the leading cause of death worldwide and is projected to increase 45% between 2007 and 2030, which will involve more than 15 … Continue Reading The first epigenetic test to diagnose tumours of unknown origin.
The inflammatory response is an integral part of the innate immune mechanism that is triggered in response to a real or perceived threat to tissue homeostasis, with a primary aim … Continue Reading New class of molecule identified in central role of inflammation and the immune system.
Generally, researchers divide the human immune system into two parts. One part, called the innate immune system, allows for immediate and direct recognition of invading bacteria. It prompts immune cells … Continue Reading Study identifies previously unknown mechanism of the immune system.
The purpose of blinks is to keep the eyes hydrated and to protect them. Blinks are rarely noticed by the subject as blink-induced alterations of visual input are blanked out … Continue Reading Researchers identify a new eye movement in human studies.
Diabetes is a chronic condition that causes high blood sugar levels that are potentially fatal if left unmanaged. Injection of insulin is the primary treatment against this disease. Unfortunately a … Continue Reading New insulin pill successful in animal studies.
It is known that nerves in the central nervous system of adult mammals do not usually regenerate when injured. However, the granule cell, a nerve cell located in the cerebellum, … Continue Reading Key molecule in the elusive regeneration of cerebellum synaptic connections identified.
During a heart attack, clots or narrowed arteries block blood flow, harming or killing cells within the tissue. However, the damage doesn’t end after the crushing pain subsides. The heart’s … Continue Reading Injectable gel used to prevent heart failure in animal model after heart attack.
For decades, scientists have known that people with two copies of a gene called apolipoprotein E4, or ApoE4, are much more likely to have Alzheimer’s disease at age 65 than … Continue Reading Study shows why people with the ApoE4 gene are more susceptible to Alzheimer’s disease.
Demyelinating diseases, such as multiple sclerosis and leukodystrophy, are characterized by damage to the protective myelin sheath that surrounds the axons of neurons. This demyelination can be caused by an … Continue Reading Cell therapy successfully promotes axon remyelination in an animal model.
There is a clinical need for new, more effective treatments for chronic and debilitating inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. Now, a study from researchers at … Continue Reading Plant-based nanoparticles successfully treat inflammatory bowel disease in animal model.
Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge … Continue Reading Researchers image the epigenetics of the human brain for the first time ever.
About 8% of Americans have type 2 diabetes, and another 25% of the population is at risk because of obesity. Type 2 diabetes is a lifelong disease that represents an … Continue Reading Study identifies new pathway in insulin resistance.
For decades, textbooks have stated that macromolecules within living cells, such as DNA, RNA, and proteins, do not fluoresce on their own. Technology instead relies on special fluorescence dyes to … Continue Reading Textbooks upended as researchers show that DNA naturally fluoresces.