Researchers led by VIB-KU Leuven discover a population of specialized brain-resident white blood cells in the mouse and human brain, and show that the presence of these lymphocytic cells is essential for normal brain development in mice. The team states these results contribute towards the increasing recognition of the role of circulating immune cells in the brain and their involvement in a range of neurological diseases.

New role for white blood cells in the developing brain.

Our onboard computer, the brain, is a sterile environment separated from the immune system by the blood-brain barrier (BBB). Consequently, this is why the brain has its own resident immune cells, known as microglia. Microglia arise in the brain during embryonic development to evolve into self-renewing cells in later development and life. Despite this fact, overwhelming research suggests the brain is a part of the … Continue reading New role for white blood cells in the developing brain.