Alcoholism is a chronic relapsing disorder associated with compulsive drinking, loss of control over intake, and emergence of a negative emotional state during abstinence from the drug. Special emphasis has … Continue Reading Researchers target neurons involved in compulsive drinking to reverse alcohol dependence in rats.
It is known that genetics plays a role in obesity, with genes directly causing obesity in disorders such as Bardet-Biedl syndrome and Prader-Willi syndrome. However, genes and behaviour may both … Continue Reading Human study shows ‘aggressive drunk’ gene may protect carriers from obesity and associated risks.
More than one-quarter of the US population qualify as excessive alcohol consumers. Studies show that alcohol use impacts several lung diseases, with heavy consumption associated with poor clinical outcomes. Now, … Continue Reading Large-scale study shows that excessive alcohol consumption impacts breathing.
In alcoholism and addictive drugs repeated exposure triggers glutamatergic and GABAergic plasticity in many neuronal populations. The dorsomedial striatum (DMS), a brain region critically involved in addiction, contains medium spiny … Continue Reading Researchers identify and successfully activate neurons that tell the brain to stop drinking.
Excessive alcohol-use is the third leading risk factor for disease following tobacco and blood pressure. The most important include peripheral neuropathy, brain damage, alcoholic liver disease, and nutritional and metabolic … Continue Reading Hormone and neurotransmitter systems disturbed in alcoholics’ brains.
For several decades, addiction has come to be viewed as a disorder of the dopamine neurotransmitter system; however, this view has not led to new treatments. Numerous studies suggest that … Continue Reading Researchers identify specific neuron-type responsible for alcoholism.
The NIAAA defines binge drinking as a pattern of drinking that brings a person’s blood alcohol concentration to 0.08 or above. This typically occurs when men consume five or more … Continue Reading Levels of known biomarker for alcohol consumption validated for binge-drinking.
Scientists at The Scripps Research Institute (TSRI) have discovered that a brain protein has a key role in controlling binge drinking in animal models. They found that deleting the gene … Continue Reading Researchers identify brain protein responsible for controlling binge- drinking.
Researchers at The University of Texas at Austin have identified a network of genes that appear to work together in determining alcohol dependence. The findings, which could lead to future … Continue Reading Alcohol abuse linked to newly identified neurogenetic network.
Binge drinking can have lasting effects on brain pathways that are still developing during adolescence, state researchers from the University of Massachusetts Amherst and Louisiana State University. Results of their … Continue Reading Neurological adolescent binge-drinking animal model launched.
Scientists at The Scripps Research Institute (TSRI) have solved the mystery of why a specific signalling pathway can be associated with alcohol dependence. This signalling pathway is regulated by a … Continue Reading Scientists link alcohol-dependence gene to neurotransmitter.