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New technique maps life’s effects on human DNA.

Researchers at the Babraham Institute, in collaboration with the Wellcome Trust Sanger Institute Single Cell Genomics Centre, have developed a powerful new single-cell technique to help investigate how the environment … Continue Reading New technique maps life’s effects on human DNA.

Protein pushes breast cancer cells to metastasize.

‘Master-regulator’ protein which pushes breast cancer cells to metastasize is identified. Unexpected links to Alzheimer’s disease and Huntington’s disease also seen. Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists at Rockefeller University have identified a protein that makes breast cancer cells more likely to metastasize. What’s more, the protein appears to trigger cancer’s spread in part by blocking two other proteins that are normally linked to neurodegeneration, a finding that suggests these two disease processes could have unexpected ties.

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Study shows link between inflammation in maternal blood and schizophrenia in offspring.

Maternal inflammation as indicated by the presence in maternal blood of early gestational C-reactive protein, an established inflammatory biomarker, appears to be associated with greater risk for schizophrenia in offspring. Inflammation has been shown to alter brain development in previous studies, and schizophrenia is a neurodevelopmental disorder. Thus, this study provides an important link between inflammation and schizophrenia and may help the medical community to better understand the biological mechanisms that lead to this disorder.

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