Autism spectrum disorders (ASD) affect around 1% of the world’s population and are characterized by a range of difficulties in social interaction and communication. There are many different genetic mutations … Continue Reading Researchers identify a new form of autism.
Hypertension is a leading risk factor for dementia, however, the mechanisms underlying its damaging effects on the brain are poorly understood. Now, a study from researchers at Weill Cornell Medicine … Continue Reading Immune cells identified as the culprit linking hypertension and dementia.
Adult brain cancers are almost always universally fatal, due in part to the biochemical composition of the central nervous system and the blood-brain barrier, which selectively and protectively limits the … Continue Reading Animal study shows depriving deadly brain cancer of cholesterol kills tumour cells.
Alzheimer’s disease is characterized by the degeneration of neurons in the hippocampus and cortex, and the appearance of neuritic plaques and neurofibrillary tangles. Although the precise cause of Alzheimer’s disease remains … Continue Reading Researchers elevate brain protein to allay symptoms of Alzheimer’s in animal model.
Delayed deterioration of neurological function after ischemia stroke is a well-documented clinical problem. However, minimal studies exist pertaining to spinal cord blood flow and blood-spinal cord barrier (BSCB) integrity with … Continue Reading Study maps how a stroke damages the blood-spinal cord barrier.
The blood-brain barrier (BBB), a collection of cells and subcellular structures in the cerebrovascular wall that separates the circulating blood from the brain, is essential to keep brain tissue in … Continue Reading Leakages identified in the blood-brain barrier of patients with early Alzheimer’s disease.
Presently, there are limitations to drug delivery to the brain as it is tightly protected by the blood-brain barrier. The blood-brain barrier is a protective barrier which separates the circulating … Continue Reading Researchers derive first ever molecular model of critical blood-brain barrier transporter.
The blood-brain barrier represents a fundamental limitation in treating neurological disease because it prevents all neuropeptides from reaching the central nervous system (CNS). Currently, there is no efficient method to … Continue Reading New technique bypasses the blood-brain barrier to deliver neuroprotection.
In Alzheimer’s, the brain begins to change years before symptoms emerge. Detecting Alzheimer’s antibodies at the preclinical stage would give patients an opportunity to work with their physician to make … Continue Reading Researchers nearing a blood test for Alzheimer’s disease.
Alzheimer’s is the most common form of dementia globally and affects up to 40,000 people in Ireland today. It is the fourth leading cause of death in individuals over the … Continue Reading Researchers have discovered clearance of Alzheimer’s protein across the blood-brain barrier.
The formation of the neurovascular unit, blood brain-barrier tracked in real-time for the first time.
Crucial bodily functions like heart rate, blood flow, breathing and digestion are regulated by the neurovascular unit. The neurovascular unit is made up of the blood–brain barrier, blood vessels, microglia … Continue Reading The formation of the neurovascular unit, blood brain-barrier tracked in real-time for the first time.
A drug that could halt the progression of multiple sclerosis may soon be developed thanks to a discovery by a team at the CHUM Research Centre and the University of … Continue Reading New treatment blocks progression of mutliple sclerosis in animal model.
Researchers have found that an antiviral compound may protect the brain from invading pathogens. Studying West Nile virus infection in mice, researchers at Washington University showed that interferon-lambda tightens the … Continue Reading Researchers ‘block’ the West Nile virus out of the brain by tightening the blood-brain barrier.
The bacteria that sneak past the brain’s defenses to cause deadly bacterial meningitis are clever adversaries. Bacteria use various molecular tricks bacteria use to convince their host that they are … Continue Reading Study identifies ‘molecular trick’ used by bacteria to bypass the blood-brain barrier.
Researchers at the University of North Carolina have used exosomes, tiny bubbles of protein and fat produced naturally by cells, to bypass the body’s defenses and deliver a potent antioxidant … Continue Reading Researchers utilize natural exosomes to deliver Parkinson’s treatment directly to brain.
Researchers identify how the blood-brain barrier is maintained to control ‘tight junction’ function.
It has long been known that the brain is protected from alterations elsewhere in the body by a highly regulated gateway known as the blood-brain barrier, which allows only selected … Continue Reading Researchers identify how the blood-brain barrier is maintained to control ‘tight junction’ function.