The onset of ALS, also known as Lou Gehrig’s disease, is marked by the gradual degradation and eventual death of neuronal axons, the slender projections on nerve cells which transmit … Continue Reading Researchers identify the key instigator of neuron damage in sporadic and inherited ALS.
Patients suffering from so-called immune-mediated neuropathies frequently have a long medical record. As there are no diagnostic tests available to reliably diagnose the disease, the diagnosis is frequently made belatedly … Continue Reading Study identifies previously unknown cause of immune neuropathy.
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease affecting motor neurons. This fatal disease is characterized by progressive muscular atrophy and doesn’t have an effective treatment. Patients with … Continue Reading Study provides first definitive evidence and description of protein clump toxicity in ALS.
A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If not, the defective … Continue Reading Researchers identify the role mitochondria plays in familial ALS.
Almost a decade ago scientists first described the clumps of TDP-43 that commonly appear in the degenerated brain or nerve cells of those with FTD or ALS. However, whether the … Continue Reading Researchers identify the mechanism of protein clumps in the brain of patients with ALS.
Researchers identify protein in the brain which inhibits key enzyme implicated in Alzheimer’s disease.
The need for a new approach to treatment of Alzheimer’s disease is urgent. Alzheimer’s is the most common age-related dementia and the number of cases in the United States is … Continue Reading Researchers identify protein in the brain which inhibits key enzyme implicated in Alzheimer’s disease.
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells responsible for controlling voluntary muscles. The disease doesn’t usually impair a person’s mind … Continue Reading New details uncovered about the genetic cause of ALS.
Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers discovered that increasing levels of a … Continue Reading Researchers identify previously unknown neuroprotective pathway in ALS.
Researchers at the University of Toronto have uncovered new insights on the genetic causes of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease. These findings could uncover a … Continue Reading Human generational study pinpoints epigenetic cause of Amyotrophic Lateral Sclerosis (ALS).
Genetics may play a larger role in causing Lou Gehrig’s disease than previously believed, potentially accounting for more than one-third of all cases, according to one of the most comprehensive … Continue Reading New neurogenetic origins of Lou Gehrig’s disease uncovered.
Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis, or ALS, might damage muscle-controlling nerve cells in the brain earlier in the disease process than previously known, according to research … Continue Reading New point of origin identified for Amyotrophic Lateral Sclerosis (ALS).
Using a technique that illuminates subtle changes in individual proteins, chemistry researchers at Cornell and Scripps Research Institute have uncovered new insight into the underlying causes of Amyotrophic Lateral Sclerosis (ALS). … Continue Reading Cornell scientists show that ALS is a protein aggregation disease.
A new study led by scientists from The Scripps Research Institute (TSRI) suggests a cause of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. The work supports a … Continue Reading Scientists link ALS progression to increased protein instability.
Researchers from the Rita Levi Montalcini Department of Neuroscience have identified blood biomarkers for Amyotrophic Lateral Sclerosis (ALS). The team identified the blood biomarkers serum albumin and creatinine as being … Continue Reading Biomarkers identified for Lou Gehrig’s disease.