The blood-brain barrier (BBB), a collection of cells and subcellular structures in the cerebrovascular wall that separates the circulating blood from the brain, is essential to keep brain tissue in … Continue Reading Leakages identified in the blood-brain barrier of patients with early Alzheimer’s disease.
It is known that during disease, tau protein gets modified, changes its location in nerve cells and then aggregates. In healthy nerve cells, tau resides in a part of the … Continue Reading Previously unknown tau pathway leading to Alzheimer’s disease identified.
In Alzheimer’s, a build-up of plaque and dysfunctional proteins in the brain are known to be hallmarks of the disease. While the majority of Alzheimer’s research has focused on accumulation … Continue Reading New technique reveals that tau predicts Alzheimer’s disease progression.
Brain map researchers release first of it’s kind data on the aging human brain and traumatic brain injury.
Dementia is a common illness with an incidence that is rising as the aged population increases. A multitude of neurodegenerative illnesses have an associated dementia, including corticobasal degeneration, Creutzfeldt–Jakob disease, … Continue Reading Brain map researchers release first of it’s kind data on the aging human brain and traumatic brain injury.
A major problem of Alzheimer’s disease diagnosis is by the time the first clinical symptoms appear, massive irreversible damage to the brain has already occurred. At that point, symptomatic treatment … Continue Reading New infrared sensor extracts amlyloid-beta from blood for early detection of Alzheimer’s.
Dendritic spines are specialized protrusions responsible for receiving excitatory synaptic inputs, providing an important function in communication between neurons. The majority of excitatory synapses in the brain exist on dendritic … Continue Reading Novel molecule promotes the neuronal structures associated with memory to grow.
The human brain has a prodigious demand for energy, it uses 20 to 30% of the body’s energy budget. In the course of normal aging, in people with neurodegenerative diseases … Continue Reading Researchers use dietary supplement to re-energize aging brains in animal model.
Primary progressive aphasia (PPA) is a form of dementia characterized by degeneration of the language network. In the early stages, PPA is associated with a left-lateralized pattern of cortical atrophy … Continue Reading Neuroimaging can identify start and location of amyloid plaques in living brain.
With Alzheimer’s disease medical professionals have to conduct costly brain imaging scans, and sometimes, invasive cerebral spinal fluid tests to rule out other diseases. Now, a new study from researchers … Continue Reading Human study identifies biomarker in blood for Alzheimer’s disease.
Alzheimer’s disease poses a health problem of pandemic proportions. It is estimated that by the year 2030 there will be greater than 60 million people worldwide with AD, and $375 … Continue Reading Newly identified role for ApoE explains its effects in Alzheimer’s.
Alzheimer’s disease is a progressive illness that is the leading cause of dementia and the sixth leading cause of death in the United States. There is no cure for the … Continue Reading Neuroimaging links two Alzheimer’s risk genes to brain atrophy, promising blood markers.
The standard model of natural selection predicts that once the age of reproduction ends, individuals die. That’s because selection early in life strongly favors variants that benefit reproductive success, even … Continue Reading Study identifies gene variants which protect older adults from neurodegeneration.
Aging is a major risk factor for many human diseases, and in vitro generation of human neurons is an attractive approach for modeling aging-related brain disorders. While aggressive familial early … Continue Reading New technique enables researchers to grow old human brain cells for the first time.
Down syndrome (DS) results from the trisomy of chromosome 21 in humans and is the most common cause of genetically defined intellectual disability. Among the various triplicate genes in DS … Continue Reading Study identifies new link between Down syndrome and Alzheimer’s disease.
Biomarkers, such as those sought for Alzheimer’s disease, are benchmarks in the body that can be reliably measured to indicate the presence or absence of a disease, or the likelihood … Continue Reading Earliest-ever diagnosing tool for Alzheimer’s becomes international standard.
Alzheimer’s is a devastating disease whose incidence is on the rise globally. ApoE-4, a particular allele of the apolipoprotein apoE, is a known risk factor. Since apoE plays a critical … Continue Reading Women with Alzheimer’s-risk gene lose weight more sharply after age 70.