It has long been known that the brain is protected from alterations elsewhere in the body by a highly regulated gateway known as the blood-brain barrier, which allows only selected molecules to pass through.  In certain diseases, however, such as multiple sclerosis, the barrier can be improperly breached. These ‘leaks’ can allow immune cells and inflammatory molecules to pass through, causing inflammation that may lead … Continue reading Researchers identify how the blood-brain barrier is maintained to control ‘tight junction’ function.