Adult brain cancers are almost always universally fatal, due in part to the biochemical composition of the central nervous system and the blood-brain barrier, which selectively and protectively limits the … Continue Reading Animal study shows depriving deadly brain cancer of cholesterol kills tumour cells.
In oncology, the Warburg effect is the observation that that the driver of tumourigenesis is an insufficient cellular respiration caused by insult to mitochondria. It postulates that most cancer cells, … Continue Reading Study uncovers vital Warburg effect pathway in brain tumour formation and metabolism.
Diffuse gliomas represent 80% of all malignant brain tumours. Adult diffuse gliomas are classified and graded according to histological criteria. However, although histopathology classification is well established it suffers from unstandardized, … Continue Reading Large-scale study identifies new epigenetic subtypes of brain cancer.
A glioma is a type of tumour that starts in the brain or spine. It is called a glioma because it arises from glial cells. The most common site of … Continue Reading First ever study shows how astrocytes help to spread glioma.
After generating new brain tumour models researchers at Cedars-Sinai have identified the previous unknown role of a family of genes underlying tumour growth in a wide spectrum of high grade … Continue Reading Researchers identify genes critical for high grade brain tumour growth.
Cancer’s ability to grow unchecked is often attributed to cancer stem cells, a small fraction of cancer cells that have the capacity to grow and multiply indefinitely. How cancer stem … Continue Reading Researchers begin to map the epigenetic tags of glioblastoma.
Magnetic nanoparticles can open the blood-brain barrier and deliver molecules directly to the brain, state researchers from the University of Montreal, Polytechnique Montréal and CHU Sainte-Justine. This barrier runs inside almost … Continue Reading Radio-controlled nanobots open the blood-brain barrier just the right amount in murine studies.
An experimental drug that attacks brain tumour tissue by crippling the cells’ energy source called the mitochondria has passed early tests in animal models and human tissue cultures, state researchers … Continue Reading Selective mitochondrial chemotherapy, decimates brain tumours and headed for human trials.
Brain cancer patients may live longer thanks to a new cancer-detection method developed by researchers at the Montreal Neurological Institute, McGill University and the Polytechnique Montréal. The collaborative team has … Continue Reading Revolutionary probe enables surgeons to detect all invasive brain cancer cells during surgery.
The brain is protected by a barrier of cells that tightly regulates the transport of substances into this organ in order to prevent infection. The essential protective function of this … Continue Reading New ‘shuttle’ can cross the blood-brain barrier and transport substances into the brain.