A research group from Helmholtz Zentrum München has developed an assay whereby mini-breasts in-a-dish can be grown, with cultured human breast epithelial cells rebuilt into the three-dimensional tissue architecture of the … Continue Reading Researchers grow mini breast-in-a-dish, provide breakthrough in breast cancer proliferation.
The chances of being cured of breast cancer have increased in recent decades, however if the tumour has metastasised, the disease remains essentially incurable. One reason for this could be … Continue Reading New cell-free circulating DNA blood test for breast cancer successful in human trials.
For years, scientists have been puzzled by the presence of short stretches of genetic material floating inside a variety of cells, ranging from bacteria to mammals, including humans. These fragments … Continue Reading Researchers identify new role for tRNA fragments in tumour suppression.
Compared to other types of breast cancer, triple negative breast cancers are often more aggressive and have fewer treatment options. In a new study published in the journal Proceedings of … Continue Reading Researchers characterise the unique nutrient needs of triple negative breast cancer.
In a study involving more than 31,000 women with cancer-causing mutations in the BRCA1 or BRCA2 genes, researchers at The Basser Center for BRCA, the Abramson Cancer Center, and the … Continue Reading Large-scale study shows risk of breast and ovarian cancer differs by type of BRCA1, BRCA2 mutation.
Researchers at UT Southwestern Medical Center have uncovered how the body’s inflammatory response can alter how estrogen promotes the growth of breast cancer cells. The researchers have identified how a … Continue Reading Researchers identify new epigenetic pathway driving breast cancer progression.
A protein commonly found in human cells could be an important switch that activates cancer cell metastasis, according to a new study by researchers at the Montreal Neurological Institute and … Continue Reading A new mechanism driving spread of cancer has been identified.
Tumours require blood to emerge and spread. That is why scientists at The University of Texas MD Anderson Cancer Center believe that targeting blood vessel cells known as pericytes may … Continue Reading Breast cancer metastasis slowed by targeting cells that regulate blood flow.
A new study from the Albert Einstein College of Medicine and the University of Pittsburgh details how cells with low levels of the profilin 1 protein in breast tumours increase their … Continue Reading Researchers identify protein crucial for breast cancer metastasis ‘scaffolding’.
Cancers that have spread throughout the body, a process known as metastasis, are difficult, often impossible, to control. They are the leading cause of cancer-related deaths. Twenty years ago, however, … Continue Reading Researchers use precision medicine-based microRNAs to limit cancer metastases.
A team of researchers led by Duke Cancer Institute have identified key events that prompt certain cancer cells to develop resistance to otherwise lethal therapies. By mapping the points of … Continue Reading Researchers begin to map epigenetic methylation in specific cancer drug resistance.
UT Southwestern Medical Center researchers have demonstrated that whole-genome sequencing can be used to identify patients’ risk for hereditary cancer, which can potentially lead to improvements in cancer prevention, diagnosis, … Continue Reading Researchers confirm whole-genome sequencing can identify cancer-related mutations and risk.
Results of the EORTC10085/TBCRC/BIG/NABCG International Male Breast Cancer Program conducted in both Europe and in the United States and presented at the 2014 San Antonio Breast Cancer Symposium found significant … Continue Reading Study finds that male and female breast cancers differ genetically.
Researchers from Institut d’Investigació Biomèdica de Bellvitge (IDIBELL) have established the epigenetic patterns of breast cancer and also its clinical consequences. The opensource study is published in the journal Molecular … Continue Reading New breast cancer classification based on epigenetics.
Researchers from Boston Children’s Hospital and Massachusetts Institute of Technology have developed a targeted drug-delivery system that’s based on a combination of ultraviolet (UV) light and short, single strands of DNA … Continue Reading Researchers use DNA paired with light to deliver drugs on target.
Molecules called long non-coding RNAs (lncRNAs) have been implicated in breast cancer but exactly why they cause metastasis and tumour growth has been little understood, until now. Scientists at The … Continue Reading Hedgehog signalling pathway for breast cancer identified.