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Categorychronic pain

Pain-initiating function of glial cells identified for the first time.

Pain hypersensitivity can spread to unaffected body regions immediately surrounding the initial insult. Sometimes it can even spread to the opposite site of the body or to large body areas … Continue Reading Pain-initiating function of glial cells identified for the first time.

Researchers link microglia activation triggered by chronic pain to anxiety and depression.

Brain inflammation caused by chronic nerve pain alters activity in regions that regulate mood and motivation, suggesting for the first time that a direct biophysical link exists between long-term pain … Continue Reading Researchers link microglia activation triggered by chronic pain to anxiety and depression.

Researchers use A3 adenosine receptors to activate ‘off signals’ for chronic pain.

In a new study from Saint Louis University, researchers discovered that drugs targeting the A3 adenosine receptor can turn off pain signals in the spinal cord to provide relief from … Continue Reading Researchers use A3 adenosine receptors to activate ‘off signals’ for chronic pain.

Cannabinoid CB2 receptors suppress neuropathic pain with no signs of physical dependence in study.

Medical marijuana is proliferating across the country due to the ability of cannabis ingestion to treat important clinical problems such as chronic pain. However, negative side effects and the development … Continue Reading Cannabinoid CB2 receptors suppress neuropathic pain with no signs of physical dependence in study.

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