The human gut contains trillions of bacteria, known as the microbiota, which play a crucial role in digesting food and regulating the immune system. Multiple studies show certain bacteria and … Continue Reading Early-life exposure to microbiota restricts colon cancer later in life.
It is known that the formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. The large-scale appearance of … Continue Reading Previously unknown gene mutation in hereditary colon cancer identified.
The pandemic of physical inactivity is associated with a range of chronic diseases and early deaths. Despite the well documented disease burden, the economic burden of physical inactivity remains unquantified … Continue Reading Physical inactivity cost the world $67 billion in 2013 says first ever estimate.
Deoxyribonucleic acid (DNA) is a molecule that contains the genetic information to develop and maintain life. DNA consists of four bases, namely adenine, cytosine, guanine, and thymine. These four bases … Continue Reading Misregulation of DNA building blocks mapped in colon cancer development.
It is known that the cells inside a malignant cancer tumour differ a lot. While some cancer cells do not cause trouble, others become aggressive and start to spread, or … Continue Reading Protein which characterises and regulates the spread of aggressive cancer cells identified.
It is known that chronic inflammation in the gut increases the risk of colon cancer by as much as 500%. Therefore, the genetic basis and mechanism of cancer proliferation in … Continue Reading Researchers show how gut inflammation initiates colon cancer.
A leading cause of cancer deaths worldwide, colon cancer is famously resistant to treatment. One reason for this is a group of persisting cancer cells in the colon that cause … Continue Reading Researchers use vitamin A to prevent relapsing colon cancer.
Colon cancer is one of the leading causes of cancer-related deaths worldwide, and researchers are hard at work to understand the disease’s complex molecular underpinnings. Now, a study from researchers … Continue Reading Newly identified gene pair in colon cancer challenges whole paradigm on causation.
Methylation is a process where a methyl group is added into critical points along human DNA. In cancer, many regions of the DNA are not methylated, leading to untimely gene … Continue Reading Researchers identify an epigenetic mechanism for colon cancer proliferation.
A main barrier to immune therapy success has been the tumour’s ability to keep the immune system from functioning against the cancer. The immune cells are there, however, like an … Continue Reading Researchers use ‘demethylating’ precision medicine to fight cancer.
Colon cancer is often detected in its earliest stages thanks in part to screening technologies like colonoscopy. By snaking a camera through a patient’s intestines, doctors can identify polyps and … Continue Reading New nanotech contrast enables blood test for precancerous growth in colon cancer.
While the overall rate of colorectal cancer is declining, previous studies show that colorectal cancer specifically among young patients is increasing. Results also show that colorectal cancer in patients younger … Continue Reading Human study shows colorectal cancer genetically different in older and younger patients.
Long non-coding RNAs (lncRNA) are unusual in that they don’t encode proteins like normal RNA. Yet they do play a role in regulating cellular functions and interest cancer researchers. Now, … Continue Reading Researchers identify long non-coding RNA which modulates colorectal cancer metabolism.
The micro RNA miR-22 has long been known for its ability to suppress cancer. However, questions remain about how it achieves this feat. For example, which molecules are regulating miR-22, … Continue Reading Researchers being to map the epigenetic pathway of miR-22 cancer suppression.
In a group of patients diagnosed with colorectal cancer at 40 or younger, 1.3 percent of the patients carried germline TP53 gene mutations, although none of the patients met the … Continue Reading Researchers begin to map inherited gene mutations in colorectal cancer.
Microbes in the human body are estimated to outnumber human cells by 10 to 1, yet research on how they affect health is still in its infancy. A perspective article … Continue Reading Swallowable gas capsule could be used to measure intestinal gas to diagnose disease.