Hypertension is a leading risk factor for dementia, however, the mechanisms underlying its damaging effects on the brain are poorly understood. Now, a study from researchers at Weill Cornell Medicine … Continue Reading Immune cells identified as the culprit linking hypertension and dementia.
Study shows that structure of toxic tau aggregates determines type of dementia, and rate of progression.
Recent efforts to develop a treatment for Alzheimer’s disease and other dementias have focused heavily on removing toxic tau proteins from the brain. The tau protein is known to bind … Continue Reading Study shows that structure of toxic tau aggregates determines type of dementia, and rate of progression.
Alzheimer’s disease is characterized by the degeneration of neurons in the hippocampus and cortex, and the appearance of neuritic plaques and neurofibrillary tangles. Although the precise cause of Alzheimer’s disease remains … Continue Reading Researchers elevate brain protein to allay symptoms of Alzheimer’s in animal model.
The CDC estimates that more than 1.3 million Americans visit an emergency department each year because of a TBI-related injury. The late effects of TBI are of great interest, however, … Continue Reading Largest ever study identifies link between TBI and Parkinson’s, but not Alzheimer’s.
Alzheimer’s disease (AD) is common and highly heritable with many gene variants associated with it. However, the genetic risk for AD have not been clearly delineated, with the stage of … Continue Reading Study identifies a genetic risk score for Alzheimer’s disease in young adults.
The hippocampus is a critical structure for encoding of novel experiences. A particularly compelling puzzle is how the hippocampus encodes new information in the presence of interference from past memories. … Continue Reading Neuroimaging shows how the brain switches from past to present memory mode.
It is known that during disease, tau protein gets modified, changes its location in nerve cells and then aggregates. In healthy nerve cells, tau resides in a part of the … Continue Reading Previously unknown tau pathway leading to Alzheimer’s disease identified.
In Alzheimer’s, a build-up of plaque and dysfunctional proteins in the brain are known to be hallmarks of the disease. While the majority of Alzheimer’s research has focused on accumulation … Continue Reading New technique reveals that tau predicts Alzheimer’s disease progression.
Brain map researchers release first of it’s kind data on the aging human brain and traumatic brain injury.
Dementia is a common illness with an incidence that is rising as the aged population increases. A multitude of neurodegenerative illnesses have an associated dementia, including corticobasal degeneration, Creutzfeldt–Jakob disease, … Continue Reading Brain map researchers release first of it’s kind data on the aging human brain and traumatic brain injury.
Dendritic spines are specialized protrusions responsible for receiving excitatory synaptic inputs, providing an important function in communication between neurons. The majority of excitatory synapses in the brain exist on dendritic … Continue Reading Novel molecule promotes the neuronal structures associated with memory to grow.
Primary progressive aphasia (PPA) is a form of dementia characterized by degeneration of the language network. In the early stages, PPA is associated with a left-lateralized pattern of cortical atrophy … Continue Reading Neuroimaging can identify start and location of amyloid plaques in living brain.
The incidence of HIV-associated dementia has declined dramatically since the introduction of potent combined antiretroviral therapy; however, milder forms of HIV-associated neurocognitive disorders (HAND) persist. Some 30 to 50 % of … Continue Reading Study shows how neural networks adapt to the presence of a toxic HIV protein.
Alzheimer’s disease is a progressive illness that is the leading cause of dementia and the sixth leading cause of death in the United States. There is no cure for the … Continue Reading Neuroimaging links two Alzheimer’s risk genes to brain atrophy, promising blood markers.
The standard model of natural selection predicts that once the age of reproduction ends, individuals die. That’s because selection early in life strongly favors variants that benefit reproductive success, even … Continue Reading Study identifies gene variants which protect older adults from neurodegeneration.
Aging is a major risk factor for many human diseases, and in vitro generation of human neurons is an attractive approach for modeling aging-related brain disorders. While aggressive familial early … Continue Reading New technique enables researchers to grow old human brain cells for the first time.
An estimated seven to ten million people worldwide are living with Parkinson’s disease (PD), which is an incurable and progressive disease of the nervous system affecting movement and cognitive function. … Continue Reading Study first to link immunogenetics to non-familial Parkinson’s disease.