Critically, the growth of children’s bones depends on growth plates situated close to the end of all long bones in the body. These plates are narrow discs of cartilage providing … Continue Reading New mechanism of bone growth uncovered.
The basic human body plan, the arrangement of organs in the body, is laid down during embryonic development. Insight into the formation of this plan informs researchers re normal development … Continue Reading New 3D atlas of human embryonic growth clears up many misconceptions on development.
During exercise, muscle function needs to significantly increase; this requires that the uptake and breakdown of the two main nutrients of myofibers, glucose and fatty acids (FAs), markedly rise. The … Continue Reading First ever bone-derived hormone to affect exercise capacity identified.
Autism spectrum disorder (ASD) is a neurodevelopmental condition that manifests in early childhood and is characterized by impairments in social communication and presence of stereotyped behaviours and restricted interests, with … Continue Reading Mothers with diabetes more likely to have autism-linked anti-fetal brain autoantibodies.
Mammalian embryos start out as a small group of identical cells. Then at an early stage, some of these cells take up an internal position within the embryo. These internal … Continue Reading Researchers visualise mammalian embryo formation for the first time.
Dividing cells are prone to errors, and so they must be prepared to summon sophisticated emergency systems to deal with potential damage. One type of division-derailing mishap can occur when … Continue Reading Researchers identify previously unknown part of the ICL DNA repair pathway.
Researchers at Columbia University and Leiden University have found that children whose mothers were malnourished at famine levels during the first 10 weeks of pregnancy had changes in DNA methylation … Continue Reading Epigenomic study pinpoints critical period for prenatal nutrition in development of fetus.
Study identifies transporter proteins responsible for human’s placenta protective ability during pregnancy.
An important function of the human placenta is to protect the fetus from detrimental substances in maternal blood, such as glucocorticoids or toxins. Placental membrane-bound transporter proteins, known as multidrug … Continue Reading Study identifies transporter proteins responsible for human’s placenta protective ability during pregnancy.
OvaScience, a global fertility company focused on the discovery, development and commercialization of new treatment options, announced that the world’s first augmented baby has been born in Canada. Now, researchers … Continue Reading New IVF technique deemed successful as world’s first ‘augmented’ baby is born.
RNA is both the bridge between DNA and the production of proteins known to carry out the functions of life, guiding the amount and type of protein mades. As messenger … Continue Reading The first ever study to map splicing changes during T cell development has been published.
In a study that included approximately 95,000 children with older siblings it has been shown that receipt of the measles-mumps-rubella (MMR) vaccine was not associated with an increased risk of … Continue Reading Large-scale study finds no link between MMR vaccine and autism, even among children at higher risk.
During pregnancy, the mother supplies the fetus with nutrients and oxygen via the placenta. If placental development is impaired, this may lead to growth disorders of the embryo or to … Continue Reading Researchers discover a new signaling pathway in embryonic development.
Researchers from the NYU Langone Medical Center and New York University have demonstrated that a specialized DNA-binding protein called CTCF is essential for the precise expression of genes that control … Continue Reading Researchers identify specialized protein crucial for normal neurodevelopment.
The signal molecule, retinoic acid, is a product of vitamin A which helps to instruct how different types of tissue are to be formed in the growing embryo. For the … Continue Reading Previously unknown effect of vitamin A on embryonic development identified.
A Mount Sinai-led research team has discovered a new kind of stem cell that can become either a liver cell or a cell that lines liver blood vessels. The existence … Continue Reading Researchers discover new type of stem cell.