Epigenetics is a research field where DNA methylation or histone acetylation, as opposed to the DNA sequence, are studied as a tool for conveying traits to the next generation. Previously, … Continue Reading New type of epigenetic mark identified in the human cell nucleus.
Obesity has become a major health threat, affecting more than half a billion people worldwide in 2014. In particular, obesity increases the risk for insulin resistance, hypertension, coronary heart disease … Continue Reading Epigenetic modification which raises obesity risk and predicts fatty liver identified.
Diffuse gliomas represent 80% of all malignant brain tumours. Adult diffuse gliomas are classified and graded according to histological criteria. However, although histopathology classification is well established it suffers from unstandardized, … Continue Reading Large-scale study identifies new epigenetic subtypes of brain cancer.
As the population continues to age, the need for biological measures of age and more precise screening tests for age-related diseases is becoming increasingly urgent. Epigenetics serves as an intersection … Continue Reading New epigenetic predictor of cancer validated in human study.
Obesity is a metabolic disorder resulting from behavioral and heritable causes. Children of obese fathers are at higher risk of developing metabolic disease later in life, independent of the body … Continue Reading Study maps epigenetics of father’s weight passed on by his sperm.
DNA methylation is essential for the proper control of gene expression and cell identity, what enables cells with the same genetic material to become, for example, a nerve cell, a … Continue Reading Single-cell imaging developed which can record DNA methylation in real time.
One of the major challenges of cocaine addiction is the high rate of relapse after periods of withdrawal and abstinence. Now, new research from McGill University and Bar Ilan University reveals … Continue Reading Study shows most epigenetic changes happen in cocaine addiction during the periods of withdrawal.
Researchers from Institut d’Investigació Biomèdica de Bellvitge (IDIBELL) have established the epigenetic patterns of breast cancer and also its clinical consequences. The opensource study is published in the journal Molecular … Continue Reading New breast cancer classification based on epigenetics.
A new study from Karolinska Institutet shows that long-term endurance training in a stable way alters the epigenetic pattern in the human skeletal muscle. The researchers also found strong links … Continue Reading Researchers map epigenetic methylation in human skeletal muscle during exercise.
The genetic tumult within cancerous tumours is more than matched by the disorder in one of the mechanisms for switching cells’ genes on and off, scientists at Dana-Farber Cancer Institute … Continue Reading Disorder in epigenetics is a defining characteristic of cancer.
Scientists at the Institut de Recherches Cliniques de Montréal (IRCM) discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. The team found … Continue Reading New discovery could prevent the development of brain tumours in children.
Dartmouth researchers have found that the genetic mutation BRAFV600E , frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumour cells, but can … Continue Reading Dartmouth research links genetic mutation and melanoma progression.
Researchers from the Lunenfeld-Tanenbaum Research Institute have revealed an exciting and unusual biochemical connection. Their discovery has implications for diseases linked to mitochondria, which are the primary sources of energy … Continue Reading Researchers make scientific history with new cellular connection.
Scientists at The University of Texas have identified genetic mutations in endometrioid endometrial carcinoma (EEC), the most common form of this cancer of the uterine lining. The mutations revealed a … Continue Reading A new form of endometrial cancer has been identified.
Scientists studying depression in teens have discovered that subtle changes in a gene can predict how the brain reacts to stress, which can cause such health issues as depression, post-traumatic … Continue Reading Researchers find multiple new predictors of stress-related illnesses.
Twist, Snail, Slug. They may sound like words in a children’s nursery rhyme, but they are actually the exotic names given to proteins that can generate cells with stem cell-like … Continue Reading Protein ZEB1 promotes breast tumour resistance to radiation therapy.