Leukemia, or blood cancer, involves pathological alterations in the body’s hematopoietic system. In acute myeloid leukemia, it is specifically the bone marrow that is affected. In a healthy body, different … Continue Reading Previously unknown cell-death pathway mapped in leukemia cells.
Charcot-Marie-Tooth Disease (CMT) is a family of inherited disorders of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most … Continue Reading Researchers identify previously unknown genetic cause of inherited neuropathy.
Deoxyribonucleic acid (DNA) is a molecule that contains the genetic information to develop and maintain life. DNA consists of four bases, namely adenine, cytosine, guanine, and thymine. These four bases … Continue Reading Misregulation of DNA building blocks mapped in colon cancer development.
Mitochondria are the cellular powerplant and, reliant on nutrient status, it is known that Vitamin B turns mitochondria into cellular builders. Through vitamin B, mitochondria produce substances to make ingredients … Continue Reading Mitochondria dysfunction shown to cause vitamin b imbalance and genetic changes.
Autism spectrum disorder (ASD) represents a diverse group of neurodevelopmental conditions. The clinical presentation and outcome vary substantially. The use of genome-wide tests to provide molecular diagnosis for individuals with … Continue Reading Study identifies children with Autism who benefit from genetic testing.
Last December, researchers identified more than 1,000 gene mutations in individuals with autism, however, it was still unclear as to how these mutations increased the risk for autism. Now, UNC … Continue Reading Researchers identify the single epigenetic mutation which causes autism.
The use of medical imaging for heart disease has exploded in the past decade. These tests expose patients to a nontrivial amount of low-dose radiation. However, nobody really knows exactly … Continue Reading New technology identifies DNA damage in patients undergoing CT scanning.
Liquid biopsy of colorectal cancer shown to be more accurate than tissue biopsy in large-scale study.
Tumour genotype plays an important role in drug resistance in patients with metastatic colorectal cancer, however, the genotype obtained at diagnosis can vary after different treatment lines. Therefore, DNA analysis … Continue Reading Liquid biopsy of colorectal cancer shown to be more accurate than tissue biopsy in large-scale study.
Practically everyone gets fatter as they get older, however, according to a new study from researchers at Duke University some people can blame their genes for the extra padding. The … Continue Reading Researchers identify gene responsible for obesity and diabetes in old age.
After generating new brain tumour models researchers at Cedars-Sinai have identified the previous unknown role of a family of genes underlying tumour growth in a wide spectrum of high grade … Continue Reading Researchers identify genes critical for high grade brain tumour growth.
Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent … Continue Reading Researchers identify new gene responsible for liver disease.
New ‘can-opener’ molecule forces HIV virus open to expose vulnerable regions for antibodies to kill.
The human immunodeficiency virus (HIV) is often likened to a hermetically sealed tin can no one has yet been able to break open. Now, researchers at the University of Montreal … Continue Reading New ‘can-opener’ molecule forces HIV virus open to expose vulnerable regions for antibodies to kill.
A study tying the aging process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age-related diseases such as cancer, diabetes … Continue Reading Researchers discover key epigenetic mechanism of human aging.
Fragile X syndrome, an inherited cause of autism and intellectual disability, can have consequences even for carriers of the disorder who don’t have full-blown symptoms. Some carriers may experience social … Continue Reading New previously unseen cellular mechanism identified in Fragile X syndrome.
Mitochondrial diseases are maternally inherited genetic disorders that cause a wide spectrum of debilitating conditions and which currently have no cure. In a new opensource study published in the journal … Continue Reading Researchers successfully ‘edit’ mitochondrial DNA to prevent inherited disease in animal model.
Researchers at the University of Michigan and UC Davis have solved a genetic mystery that has afflicted three unrelated families, and possibly others, for generations. These families have been plagued … Continue Reading Researchers map rare mutation causing vitamin A deficiency and eye deformities.