Brain inflammation caused by chronic nerve pain alters activity in regions that regulate mood and motivation, suggesting for the first time that a direct biophysical link exists between long-term pain and the depression, anxiety and substance abuse seen in more than half of these patients, UC Irvine and UCLA researchers report. The opensource study is published in the Journal of Neuroscience. The team state that … Continue reading Researchers link microglia activation triggered by chronic pain to anxiety and depression.