
Orphan receptor proteins deliver 2 knock-out punches to glioblastoma cells.
Two related proteins exert a lethal double whammy effect against glioblastoma cells when activated with a small molecule, say researchers from the Georgetown Lombardi Comprehensive Cancer Center. The scientists say when activated by epigenetic methylation, one protein, called the short form, stops glioblastoma cells from replicating their DNA, and the other, called the long form, prevents cell division if the DNA has already been replicated. … Continue reading Orphan receptor proteins deliver 2 knock-out punches to glioblastoma cells.