In the female reproductive system ovarian follicles are the basic unit of the ovary, consisting of an immature egg, known as an oocyte, surrounded by granulosa cells. Besides being crucial … Continue Reading Mice born from eggs derived from the granulosa cells surrounding oocytes.
In genetic engineering and fertility, sperm sorting is a technique allowing the selection of the type of sperm cell to fertilize the egg cell with. It can be used to … Continue Reading Cheap, simple technique allows sex selection of sperm before fertilization.
Through millions of years of trained evolution, all living organisms adapt their behavior in response to infection, however, the mechanisms behind this are less understood. Now, a study led by … Continue Reading Neurons regulate reproduction in fruit flies during infection.
Preterm birth is a leading cause of infant mortality that can lead to poor life-long health and adverse neurodevelopmental outcomes. The physiologic mechanisms that precede preterm labor remain elusive, and … Continue Reading Epigenetics and environmental factors identified in preterm birth.
Now, researchers at Peter MacCallum Cancer Centre have identified a link between the BRCA1 gene mutation and lower levels of a hormone that is an indicator of the number of … Continue Reading Gene mutation implicated in cancer also linked to lower fertility in women.
In humans, the surgical removal of an ovary or ovaries is most often performed due to diseases such as ovarian cysts or cancer, or in conjunction with hysterectomy. In the … Continue Reading 3D-printed ovary bioprosthesis restores fertility in mice.
Infertility affects up to 15% of couples, with roughly one-third of all cases being caused by male infertility. One major cause of male infertility is the failure of precursor germ … Continue Reading Stem cell technique makes first ever viable sperm-in-a-dish.
Preeclampsia, which affects 5 to 8% of pregnancies worldwide, is characterized by high blood pressure and protein in the urine. The disorder is the number one reason physicians decide to … Continue Reading New field-based test for preeclampsia validated in large-scale study.
Pre-term birth is a birth which takes place before 37 weeks of pregnancy. According to the Centers for Disease Control and Prevention, in 2014, preterm birth affected one out of … Continue Reading Large-scale study successfully validates test for preterm birth risk.
The mammalian Y chromosome encodes a specialized set of genes that are essential for male viability and fertility. In particular, the sex-determining region Y (SRY) protein is necessary to initiate … Continue Reading Male mice without any Y chromosome produce offspring with assisted reproduction.
Semen quality is a measure of the ability of semen to accomplish fertilization and a measure of fertility in a man. It is the sperm in the semen that are … Continue Reading ‘Spermbots’ successful in proof-of-concept fertility studies.
A fundamental law of genetics states that progenies do not inherit epigenetically-based adaptive, pathological or neural features acquired in response to environmental conditions. However, recent studies seem to contradict this … Continue Reading Researchers map ‘epigenetic inheritability’ in fathers sperm caused by diet.
Obesity is a metabolic disorder resulting from behavioral and heritable causes. Children of obese fathers are at higher risk of developing metabolic disease later in life, independent of the body … Continue Reading Study maps epigenetics of father’s weight passed on by his sperm.
With premature birth now a persistent health problem, the need for standardised biomarkers is a necessity. Amniotic fluid (AF) both contributes to and reflects the status of the fetus, and … Continue Reading Cell-free RNA in amniotic fluid used to identify stage of human fetal organ maturity.
In general, infertility is defined as not being able to get pregnant after one year of unprotected sex. Causes of infertility or reproductive problems include disease and aging, with male … Continue Reading Researchers identify specific neurons which activate fertility master switch.
It has long been known that there is a linear connection between sperm motility and chances of becoming pregnant. Sperm motility describes the ability of sperm to move properly through … Continue Reading Study finds lower sperm motility in men exposed to a common, everyday chemical.