Recent efforts to develop a treatment for Alzheimer’s disease and other dementias have focused heavily on removing toxic tau proteins from the brain. The tau protein is known to bind … Continue Reading Study shows that structure of toxic tau aggregates determines type of dementia, and rate of progression.
Almost a decade ago scientists first described the clumps of TDP-43 that commonly appear in the degenerated brain or nerve cells of those with FTD or ALS. However, whether the … Continue Reading Researchers identify the mechanism of protein clumps in the brain of patients with ALS.
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells responsible for controlling voluntary muscles. The disease doesn’t usually impair a person’s mind … Continue Reading New details uncovered about the genetic cause of ALS.
Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers discovered that increasing levels of a … Continue Reading Researchers identify previously unknown neuroprotective pathway in ALS.
Researchers from KU Leuven have identified a new strategy for treating an inherited form of dementia after attempting to turn stem cells derived from patients into the neurons most affected … Continue Reading Patient stem cells used to make dementia-in-a-dish for the first time.
Drugs that boost the function of a specific type of neurotransmitter receptor may provide benefit to patients with the second most common type of dementia, according to research by scientists … Continue Reading Scientists boost receptor-function to treat Frontotemporal dementia.