Category Archives: Frontotemporal dementia

Study shows that structure of toxic tau aggregates determines type of dementia, and rate of progression.


Recent efforts to develop a treatment for Alzheimer’s disease and other dementias have focused heavily on removing toxic tau proteins from the brain.  The tau protein is known to bind microtubules, structures enable transport of cellular components, in neurons.  However, the protein becomes toxic in patients with Alzheimer’s and other dementias, forming aggregates that progressively accumulate and lead to loss

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