Dividing cells are prone to errors, and so they must be prepared to summon sophisticated emergency systems to deal with potential damage. One type of division-derailing mishap can occur when … Continue Reading Researchers identify previously unknown part of the ICL DNA repair pathway.
Researchers at the University of Bonn and the German Center for Infection Research (DZIF) have discovered two new groups of viruses within the Bunyavirus family in the tropical forest of … Continue Reading Researchers have discovered two new groups of viruses.
In results presented at the American Association for Cancer Research (AACR) Annual Meeting 2015, a collaborative study by the University of Colorado and the National Cancer Institute (NCI) reports that … Continue Reading Precision medicine study shows the most frequently altered gene in bladder cancer.
A small number of children who catch the influenza virus fall so ill they end up in the hospital, perhaps needing ventilators to breathe, even while their family and friends … Continue Reading Epigenetic mutation helps explain why, in rare cases, flu can kill.
Leprosy is a chronic infection of the skin, peripheral nerves, eyes and mucosa of the upper respiratory tract, affecting over a quarter million people worldwide. Its symptoms can be gruesome … Continue Reading The genomes and origins of the leprosy bacterias compared for the first time.
Columbia University Medical Center (CUMC) researchers have pinpointed the immune system mechanism that allows a kidney transplant to be accepted without lifelong immunosuppressive drugs, a significant step toward reducing or … Continue Reading Kidney transplant tolerance mechanism identified.
Genomics researchers analyzing a rare, serious immunodeficiency disease in children have discovered links to a gene crucial to the body’s defense against infections. The finding may represent an inviting target … Continue Reading Precision medicine study of CVID pinpoints gene crucial to immune defense.
Researchers at the University of Alberta and Beijing Genomics Institute have found that human betaretrovirus (HBRV) infection is commonly observed in the cells of patients with primary biliary cirrhosis (PBC), a … Continue Reading Researchers solve 40-year-old mystery of betaretrovirus infection in humans.
Notch genes are a double-edged sword, in some cancers they have a harmful effect because they promote tumour growth, whilst in others they act as tumour suppressors. The reason is … Continue Reading Researchers map Notch mutations in bladder cancer.
Researchers from the Vanderbilt University, the University of Toronto and Chronix Biomedical have demonstrated a method for detecting ‘cell-free’ tumour DNA in the bloodstream. The team believe that the technique … Continue Reading Researchers develop epigenetic ‘cell-free’ DNA blood test for prostate cancer.
Next generation sequencing in malignant pleural mesothelioma (MPM) tumours shows a complex mutational setting with a high number of genetic alterations in genes involved in DNA repair, cell survival and … Continue Reading Next generation sequencing used to map epigenetic methylation in malignant pleural mesothelioma.
An international consortium of researchers led by Baylor College of Medicine has identified for the first time a gene associated with familial glioma (brain tumours that appear in two or … Continue Reading Researchers have identified the first gene associated with familial glioma.
Panic disorder is a severe form of anxiety in which the affected individual feels an abrupt onset of fear, often accompanied by profound physical symptoms of discomfort. Scientists have known … Continue Reading Researchers begin to map the neurogenetics of panic disorder.
A new United States Army contracted study has found it is possible to distinguish between different hemorrhagic fevers, including Marburg (Ebola cousin) and Lassa before the person becomes symptomatic. The embargoed … Continue Reading RNA test diagnoses Lassa and Marburg hemorrhagic viruses before symptoms show.
An international collaboration led by Johns Hopkins University successfully established a visual mapping of the molecular pathway of myeloid derived suppressor cell (MDSC) cancer by way of an interactome. The … Continue Reading First ever genetic pathway mapped for MDSC cancer progression.
An international team of researchers has identified a new inherited neuromuscular disorder. The rare condition is the result of a genetic mutation that interferes with the communication between nerves and … Continue Reading A new rare neuromuscular disease has been discovered by researchers.