Adult brain cancers are almost always universally fatal, due in part to the biochemical composition of the central nervous system and the blood-brain barrier, which selectively and protectively limits the … Continue Reading Animal study shows depriving deadly brain cancer of cholesterol kills tumour cells.
In oncology, the Warburg effect is the observation that that the driver of tumourigenesis is an insufficient cellular respiration caused by insult to mitochondria. It postulates that most cancer cells, … Continue Reading Study uncovers vital Warburg effect pathway in brain tumour formation and metabolism.
Cancer researchers have known for years that tumours have unusual metabolisms, their rapid use of glucose is used as a diagnostic tool for tumours in PET scans. However, only recently … Continue Reading Study identifies new nutrient-based mechanism of cancer proliferation, drug resistance.
Cancer’s ability to grow unchecked is often attributed to cancer stem cells, a small fraction of cancer cells that have the capacity to grow and multiply indefinitely. How cancer stem … Continue Reading Researchers begin to map the epigenetic tags of glioblastoma.
Glioblastomas are a highly aggressive type of brain tumour, with few effective treatment options. Moffitt Cancer Center researchers are one step closer to understanding glioblastoma development following the identification of … Continue Reading Researchers map protein pathway involved in brain tumour stem cell growth.
Brain cancer patients may live longer thanks to a new cancer-detection method developed by researchers at the Montreal Neurological Institute, McGill University and the Polytechnique Montréal. The collaborative team has … Continue Reading Revolutionary probe enables surgeons to detect all invasive brain cancer cells during surgery.
A new study by Johns Hopkins researchers links a well-known cell communication pathway called Notch to one of the most common brain tumours found in children. Their study suggests the … Continue Reading Notch pathway mapped and linked to common pediatric brain tumour.
The brain is protected by a barrier of cells that tightly regulates the transport of substances into this organ in order to prevent infection. The essential protective function of this … Continue Reading New ‘shuttle’ can cross the blood-brain barrier and transport substances into the brain.
UT Southwestern Medical Center researchers have discovered that brain tumours are capable of burning acetate for fuel, providing a new potential target for halting tumour growth. The opensource study is published … Continue Reading Neuro-oncologists discover cancer cells can burn acetate for fuel.
Two related proteins exert a lethal double whammy effect against glioblastoma cells when activated with a small molecule, say researchers from the Georgetown Lombardi Comprehensive Cancer Center. The scientists say … Continue Reading Orphan receptor proteins deliver 2 knock-out punches to glioblastoma cells.
Dangerous brain tumours hijack the brain’s existing blood supply throughout their progression, by growing only within narrow potential spaces between and along the brain’s thousands of small blood vessels, new … Continue Reading Hijacking the brain’s blood supply, tumour discovery could aid treatment.
Could the body’s own immune system play a role in memory impairment and cognitive dysfunction associated with conditions like chronic epilepsy, Alzheimer’s dementia and concussions?. The study focuses on the … Continue Reading Immune response protein is a link between brain injury and brain disorders.
Researchers at the UNC School of Medicine have discovered that the protein PARC/CUL9 helps neurons and brain cancer cells override the biochemical mechanisms that lead to cell death in most … Continue Reading Neurons, brain cancer cells require the same little-known protein for long-term survival.