
Researchers block mitochondrial glucose production to treat type 2 diabetes in preclinical trials.
High blood sugar is a defining characteristic of Type 2 diabetes and the cause of many of the condition’s complications, including kidney failure, heart disease, and blindness. Most diabetes medications aim to maintain normal blood sugar (glucose) levels and prevent high blood sugar by controlling insulin. Now, a study from researchers at University of Iowa shows that another biological checkpoint, known as the Mitochondrial Pyruvate … Continue reading Researchers block mitochondrial glucose production to treat type 2 diabetes in preclinical trials.