HIV is a viral infection that is treatable using Antiretroviral Therapy (ART). ART stops HIV from replicating itself and by doing so reduces the amount of virus in the blood … Continue Reading New technique detects cells hiding dormant HIV reservoirs, wakes virus up.
Acute HIV-1 infection is the phase of HIV-1 disease immediately after infection that is characterized by an initial burst of viremia; although anti-HIV-1 antibodies are undetectable, HIV-1 RNA or p24 … Continue Reading Study captures HIV study early to successfully characterise the elusive acute infection period.
HIV, is a virus that attacks the body’s immune system. If left untreated, HIV can progress and develop into AIDS. HIV infection is enhanced by adhesive structures that form between … Continue Reading First-ever study captures HIV cell-to-cell transmission in a living animal.
The human immunodeficiency virus (HIV) is a lentivirus which causes HIV infection and over time AIDS. Developing effective prevention measures for HIV is hindered by incomplete knowledge of the phenotype … Continue Reading New technology lights up location of first cells to be infected in female HIV transmission.
Towards a universal HIV vaccine with the identification of first immature ‘elite controller’ antibody.
HIV has been hard to beat as the virus mutates rapidly and has a sturdy set of defenses, including a ‘shield’ of glycan molecules on the surface of its envelope … Continue Reading Towards a universal HIV vaccine with the identification of first immature ‘elite controller’ antibody.
A fundamental question in human immunodeficiency virus 1 (HIV-1) research is why the immune system is unable to contain the virus. Unlocking this key would provide a significant advance in … Continue Reading New study explains why HIV is not cleared by the immune system.
The earliest events that occur following mucosal HIV-1 exposure remain poorly understood, largely because the eclipse period of infection prior to the detectable disease is very difficult to study in … Continue Reading Earliest ever events following HIV infection mapped for the first time.
It is known that HIV, the causative agent of AIDS, is severely species restricted, and, to date, only humans and chimpanzees have been shown to be susceptible to infection. Human … Continue Reading First-ever study proves HIV targets & replicates in human macrophages.
Envelope glycoprotein GP120 is a glycoprotein exposed on the surface of the HIV envelope (ENV). The envelope glycoprotein trimer is essential for HIV entry into cells as it plays a … Continue Reading New breakthrough imaging shows HIV structure in unprecedented detail.
The incidence of HIV-associated dementia has declined dramatically since the introduction of potent combined antiretroviral therapy; however, milder forms of HIV-associated neurocognitive disorders (HAND) persist. Some 30 to 50 % of … Continue Reading Study shows how neural networks adapt to the presence of a toxic HIV protein.
How HIV-1 overcomes the person’s defenses and infects their cells has been studied intensively for over 30 years. While much has been learned, there remain events in the viral life … Continue Reading Researchers reveal and image new phase of HIV infection for the first time.
Over the past three decades DNA has emerged as an exceptional molecular building block for nanoconstruction due to its predictable conformation and programmable base-pairing interactions. DNA nanotechnology is the design … Continue Reading Low-cost DNA nanobot can detect many diseases, including HIV.
A young woman now aged 18 and a half, who at birth was HIV-infected via mother-to-child transmission (during pregnancy or at delivery), is in virological remission, despite not having taken … Continue Reading World’s first case of long-term remission (12 years) in an HIV-infected child to be presented.
Despite symptom-stifling anti-retroviral drugs, as many as half of all patients living with HIV experience neurological damage tied to chronic inflammation in the brain fueled by the body’s own immune … Continue Reading Study discovers the role of microglia in HIV-related neurological damage.
New ‘can-opener’ molecule forces HIV virus open to expose vulnerable regions for antibodies to kill.
The human immunodeficiency virus (HIV) is often likened to a hermetically sealed tin can no one has yet been able to break open. Now, researchers at the University of Montreal … Continue Reading New ‘can-opener’ molecule forces HIV virus open to expose vulnerable regions for antibodies to kill.
Engaging in unprotected sex with multiple partners increases the risk of contracting multiple strains of HIV, the virus that causes AIDS. Once inside a host, these strains can recombine into … Continue Reading A previously unclassified aggressive form of HIV discovered in Cuba.