Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health, leading to reduced life expectancy and … Continue Reading Researchers link obesity to a faulty immune system in animal model.
Alzheimer’s is the most common form of dementia, causing problems with memory, thinking and behaviour. Symptoms usually develop slowly and get worse over time as it is a progressive disease; … Continue Reading Largest ever human trial shows resveratrol impacts Alzheimer’s biomarker.
Premature birth is the birth of a baby at less than 37 weeks gestational age. Risk factors include diabetes, high blood pressure, being pregnant with more than one baby, being … Continue Reading Researchers identify a molecule which prevents preterm birth/labour.
Rheumatoid arthritis (RA) is the most common inflammatory of the types of arthritis affecting around 1% of the population. RA is an autoimmune disease that causes inflammation, pain, stiffness and … Continue Reading Gene regulating severity of tissue damage in rheumatoid arthritis identified.
To be activated, T cells must first recognize an antigen, receive appropriate costimulatory signals, and then encounter inflammatory cytokines to expand the immune response. This immune response has been harnessed … Continue Reading New T-cell regulation discovery set to rewrite immunology text books.
The immune system not only responds to infections and other potentially problematic abnormalities in the body, it also contains a built-in brake in the form of regulatory T cells. These … Continue Reading Researchers identify a previously unknown regulator of the immune system.
It’s been known that in the presence of obesity, the endoplasmic reticulum (ER) dysfunction is unable to perform one of its key functions: initiating a cascade of intracellular events called … Continue Reading New obesity-related mechanism identified in the development of Type 2 diabetes.
A young woman now aged 18 and a half, who at birth was HIV-infected via mother-to-child transmission (during pregnancy or at delivery), is in virological remission, despite not having taken … Continue Reading World’s first case of long-term remission (12 years) in an HIV-infected child to be presented.
A new neuroimaging study has shown that in just two years people with type 2 diabetes experienced negative changes in their ability to regulate blood flow in the brain This … Continue Reading Long-term human study shows detrimental effect diabetes has on brain plasticity.
Through studying brain scans and cerebrospinal fluid of healthy adults researchers at Washington University have shown that changes in key biomarkers of Alzheimer’s disease during midlife can help identify those who … Continue Reading First ever large-scale human study validates multiple biomarkers for Alzheimer’s disease.
There is currently great interest in treating ulcerative colitis with fecal microbiota transplantation (FMT), which involves transplanting gut fecal bacteria from healthy people into patients with ulcerative colitis. Now, two new … Continue Reading First ever trial of fecal microbiota transplantation in humans with ulcerative colitis successful.
Current asthma medications, which work by suppressing inflammatory signaling by immune cells or by dilating the airways, can stop working over time. Now, a new study from Boston Children’s Hospital, … Continue Reading Study successfully targets nerve endings to curb allergic asthma in animal model.
Researchers at the University of Kentucky have completed a study that revealed differences in the way neuroinflammation, considered a key component of Alzheimer’s disease, is expressed in different subsets of … Continue Reading Study finds Alzheimer’s disease presents differently in patients with Down syndrome.
The results of a study presented today at the European League Against Rheumatism Annual Congress revealed that DNA methylation, a mechanism that regulates gene expression, could influence the progression of … Continue Reading First ever study maps the epigenetics of AS development caused by environmental factors.
Involuntary childlessness is common, and in half of all cases attributable to infertility in the man. Although male infertility has many possible causes, it often remains unexplained. Now, a new … Continue Reading Researchers identify new cause of male infertility in human studies.
Brain inflammation caused by chronic nerve pain alters activity in regions that regulate mood and motivation, suggesting for the first time that a direct biophysical link exists between long-term pain … Continue Reading Researchers link microglia activation triggered by chronic pain to anxiety and depression.