Leukemia, or blood cancer, involves pathological alterations in the body’s hematopoietic system. In acute myeloid leukemia, it is specifically the bone marrow that is affected. In a healthy body, different … Continue Reading Previously unknown cell-death pathway mapped in leukemia cells.
The intestines’ primary role is digestion, however, they must also achieve high performance around the clock defending against pathogens and environmental pollutants. This is because everything taken up with food … Continue Reading Study shows how an important intestinal immune response controller works.
Type 1 diabetes is an autoimmune disease, meaning that the underlying problem is with the immune system. It is still unclear as to why the body’s immune system attacks and … Continue Reading Salmonella-based oral vaccine for T1 diabetes successful in animal model.
Psoriasis is a chronic autoimmune disorder that affects 2% of the world population. It is characterised by inflammation and scaling of the skin, accompanied by a greater risk of contracting … Continue Reading Researchers identify a link between psoriasis and bone loss.
A primary function of cytokines is to initiate immune responses; however, it has become increasingly apparent that they play major roles in the regulation of energy homeostasis, implicating them in … Continue Reading Sensor protein shown to have dual role in immune-system and metabolism.
Tumours are known to evade the immune system by a variety of mechanisms, one of which is the recruitment of ‘myeloid-derived suppressor cells’ (MDSC). MDSCs suppress the ability of the … Continue Reading Researchers uncover more about the elusive pericyte-tumour interaction.
Premature birth is the birth of a baby at less than 37 weeks gestational age. Risk factors include diabetes, high blood pressure, being pregnant with more than one baby, being … Continue Reading Researchers identify a molecule which prevents preterm birth/labour.
First comprehensive study of genetic risks for Inflammatory Bowel Disease (IBD) in African-Americans performed.
Crohn’s disease and ulcerative colitis are chronic autoimmune diseases that affect as many as 1.6 million Americans. Patients with Inflammatory Bowel Disease (IBD) have immune systems that attack their own … Continue Reading First comprehensive study of genetic risks for Inflammatory Bowel Disease (IBD) in African-Americans performed.
To be activated, T cells must first recognize an antigen, receive appropriate costimulatory signals, and then encounter inflammatory cytokines to expand the immune response. This immune response has been harnessed … Continue Reading New T-cell regulation discovery set to rewrite immunology text books.
Type 1 diabetes is an autoimmune disease, which primarily surfaces in childhood, where the immune system attacks the insulin-producing cells of the pancreas, leaving children facing a lifetime of daily … Continue Reading Lower levels of four proteins crucial for immune response found in T1 diabetes patients.
Current asthma medications, which work by suppressing inflammatory signaling by immune cells or by dilating the airways, can stop working over time. Now, a new study from Boston Children’s Hospital, … Continue Reading Study successfully targets nerve endings to curb allergic asthma in animal model.
Tuberculosis is caused by the bacterium Mycobacterium tuberculosis and it affects over 12 million people globally. When the bacterium infects a person, the body’s immune response is critical to how … Continue Reading Researchers identify how tuberculosis uses precision medicine to trick the immune system.
Study identifies transporter proteins responsible for human’s placenta protective ability during pregnancy.
An important function of the human placenta is to protect the fetus from detrimental substances in maternal blood, such as glucocorticoids or toxins. Placental membrane-bound transporter proteins, known as multidrug … Continue Reading Study identifies transporter proteins responsible for human’s placenta protective ability during pregnancy.
About 15% of patients with Lyme disease develop peripheral and central nervous system involvement, often accompanied by debilitating and painful symptoms. Now, researchers from Tulane National Primate Research Center and Louisiana … Continue Reading Researchers map neuroinflammation and nervous system manifestations of Lyme disease.
A three-character code brings relief to patients with psoriasis and sheds light on complex immunoregulation processes, IL-4, an abbreviation for the endogenous signaling molecule Interleukin 4. The substance’s ability to … Continue Reading Researchers harness the body’s own immune system to counteract psoriasis.
Doctors treating patients battling both HIV and tuberculosis (TB), many of whom live in Africa, are faced with the decision when to start those patients on antiretroviral therapy (ART) while … Continue Reading Newly identified blood biomarkers predict early death, complications in HIV patients with TB.