The neuronal gene Arc is essential for long-lasting information storage in the brain, mediating various forms of synaptic plasticity and is implicated in neurodevelopmental disorders. However, little is known about … Continue Reading Previously unknown method of neurotransmission identified.
During neurodevelopment, the brain fabricates an incredible number of neurons which then migrate to specific parts of the brain. The development of new neurons is active all the way through … Continue Reading Study identifies how adult brain circuits regulate new neuron production.
The human brain is the source of a person’s thoughts, emotions, perceptions, actions, and memories. One challenge for neuroscience is to achieve an integrated understanding of brain-wide interactions, particularly the … Continue Reading Study identifies new function for the hippocampus.
Marijuana is a psychoactive sedative drug and is derived from the hemp plant, Cannabis sativa. Its leaves and buds can be smoked, taken in food, brewed in tea or taken … Continue Reading Neuroimaging shows that marijuana users have low blood flow to the brain.
Despite the global medical community’s understanding of the significance of the prefrontal cortex in the consolidation of long-term memories, its role in the encoding of long-term memory remains elusive. Now, a … Continue Reading New study identifies region of brain responsible for conditioned fear memory.
It is known that neurons in the central nervous system of higher vertebrates are formed during embryonic development and that neurogenesis does not occur postnatally, except in the hippocampus. Buried … Continue Reading Researchers sucessfully make memories stronger and more precise during aging in mice.
Alzheimer’s disease is characterized by the degeneration of neurons in the hippocampus and cortex, and the appearance of neuritic plaques and neurofibrillary tangles. Although the precise cause of Alzheimer’s disease remains … Continue Reading Researchers elevate brain protein to allay symptoms of Alzheimer’s in animal model.
Exercise is well-known for its cognitive benefits because it causes neurogenesis, the creation of new neurons, in the hippocampus, which is a key brain region for learning, memory and mood … Continue Reading Research refutes famous study, shows neurons created through exercise don’t erase old memories.
Alzheimer’s disease (AD) is common and highly heritable with many gene variants associated with it. However, the genetic risk for AD have not been clearly delineated, with the stage of … Continue Reading Study identifies a genetic risk score for Alzheimer’s disease in young adults.
In alcoholism and addictive drugs repeated exposure triggers glutamatergic and GABAergic plasticity in many neuronal populations. The dorsomedial striatum (DMS), a brain region critically involved in addiction, contains medium spiny … Continue Reading Researchers identify and successfully activate neurons that tell the brain to stop drinking.
It is known that one of the earliest sites of Alzheimer’s disease pathology is the hippocampus, a brain structure critical for the learning and memory processes that falter early in Alzheimer’s … Continue Reading Study shows how Alzheimer’s risk gene disrupts memory replay.
Performance of cognitive tasks requires reallocation of resources within and among cortical networks. Understanding the molecular mechanisms that govern such network dynamics is a longstanding goal of cognitive neuroscience. A … Continue Reading Neuroimaging maps interaction between neural networks during working memory.
The hippocampus is a critical structure for encoding of novel experiences. A particularly compelling puzzle is how the hippocampus encodes new information in the presence of interference from past memories. … Continue Reading Neuroimaging shows how the brain switches from past to present memory mode.
NMDA glutamate receptors function as receptors which bond with glutamates, and are known to be deeply involved in memory and learning. In order for memories to be created inside the … Continue Reading Study identifies microtubule protein crucial for synaptic plasticity and memory.
Dendritic spines are specialized protrusions responsible for receiving excitatory synaptic inputs, providing an important function in communication between neurons. The majority of excitatory synapses in the brain exist on dendritic … Continue Reading Novel molecule promotes the neuronal structures associated with memory to grow.
Primary progressive aphasia (PPA) is a form of dementia characterized by degeneration of the language network. In the early stages, PPA is associated with a left-lateralized pattern of cortical atrophy … Continue Reading Neuroimaging can identify start and location of amyloid plaques in living brain.