New treatment strategy for muscular dystrophy sound in preclinical phase.

The muscular dystrophies are a group of muscle wasting disorders characterized by progressive weakening and degeneration of striated muscle. The most common form is Duchenne muscular dystrophy (DMD), an X-linked disorder caused by genetic disruption of dystrophin that affects 1 in 3,500–5,000 males.  DMD results from disruption of the dystrophin–glycoprotein complex (DGC), a structure that spans the sarcolemma and forms a mechanical linkage between the … Continue reading New treatment strategy for muscular dystrophy sound in preclinical phase.