Brazil is in the midst of an unprecedented epidemic of Zika virus (ZIKV), a flavivirus that is transmitted by mosquitoes and sexually, which was first detected in the country in … Continue Reading New research provides mechanism and evidence of how Zika virus causes microcephaly in newborns.
Proneural proteins of the class I/II basic-helix-loop-helix (bHLH) family are transcription factors that are highly conserved from invertebrates to humans. Class I bHLH proteins are expressed in a broad number … Continue Reading New role revealed for neurogenesis protein associated with schizophrenia.
Infection and inflammation during pregnancy have been associated with adverse outcomes, such as preterm birth, abortion, and postnatal cognitive disorders. Yet how microbial products circulating in the maternal bloodstream affect … Continue Reading Study shows maternal bacterial infections trigger abnormal neurogenesis in fetal brain.
The autonomic nervous system, made up of sympathetic and parasympathetic branches, is known to regulate blood glucose levels by directly controlling insulin secretion by the pancreas. Insulin secretion and blood … Continue Reading Hormone inhibits neuronal connections between the brain and pancreas in neurodevelopment.
The human brain is home to many different types of neurons with their own genetic signature to define their function. These neurons are derived from progenitor cells, which are specialized … Continue Reading The ‘neuronal big bang’ is visualised for the first time.
Autism Spectrum Disorders (ASD) are a group of highly inheritable behavioural disorders. Patients with ASD have mild to severe communication difficulties, repetitive behaviour and social challenges. Such disorders significantly challenge … Continue Reading Study identifies neurogenetics that link abnormal neurodevelopment to ASD.
Astrocytes are star-shaped cells in the brain that surround brain cells, known as neurons, protecting them from injury and enabling them to function properly. The brain contains billions of cells, … Continue Reading Study breaks new ground on the role and formation of astrocytes in the brain.
With more than 25% of high school seniors reporting recent use and 6.5% of 12th graders being daily users, marijuana (MJ) is the most frequently used illicit substance among adolescents. … Continue Reading Neuroimaging shows that young starting age of marijuana causes arrested neurodevelopment.
The human nervous system is made up of an astonishing diversity of neurons. And yet only a very small number of proteins are needed to generate and determine the identity … Continue Reading Researchers identify a previously unknown regulatory mechanism of neurogenesis.
Signs of autism, schizophrenia and bipolar disorder often take years to manifest. Studying suspect disease genes in the brain early in life could prove valuable in the development of new … Continue Reading Study maps autism-linked protein in neurodevelopment.
In the late diagnosis of autism spectrum disorder (ASD), a risk factor that has been repeatedly identified is a low birth weight or low gestational age at the time of … Continue Reading Neuroimaging identifies markers in premature babies who later develop autism.
Currently, more than 6 million children in the United States, or 11% of all children aged 4 to 17, have received attention-deficit hyperactivity disorder (ADHD) diagnoses. The disorder is characterized … Continue Reading Neuroimaging shows interactions in attention-based brain networks weaker in children with ADHD.
Large-scale study provides definitive proof that antidepressants during pregnancy increases autism risk.
Antidepressants are the first line of treatment for depression and anxiety for pregnant women, and they are able to cross the placenta. Not many studies have evaluated the effects of … Continue Reading Large-scale study provides definitive proof that antidepressants during pregnancy increases autism risk.
During embryonic development, billions of neurons nimbly reposition themselves within the brain and spinal cord, and connect branches to form the neural circuits that ultimately control our movements, perception, and … Continue Reading Previously unknown molecule critical for neurodevelopment identified.
The brain controls most of a person’s behaviour and changes in how brain areas work and communicate with each other can alter this behaviour and lead to impairments associated with … Continue Reading New neuroimaging technique shows how the ‘social brain’ is impaired in autism.
Differences in the size and structure of certain brain areas have been found in some adults diagnosed with schizophrenia. Early findings came from the discovery of enlarged ventricles in people … Continue Reading Neuroimaging matches specific schizophrenia behaviour to the brain’s anatomy.