In Kennedy’s disease, the muscle cells and motor neurons, which are also linked to muscle function, are damaged as a result of the accumulation of androgen receptor fibers, a process … Continue Reading Identification of a neuroprotector linked to a degenerative neuromuscular disease.
After suffering a stroke, which is estimated to kill more than 6 million people annually, about three-quarters of patients exhibit some disability. It is known that most strokes occur when … Continue Reading Novel neuroprotector successfully reduces brain damage after stroke in preclinical studies.
The human brain has a prodigious demand for energy, it uses 20 to 30% of the body’s energy budget. In the course of normal aging, in people with neurodegenerative diseases … Continue Reading Researchers use dietary supplement to re-energize aging brains in animal model.
In the brain, patterns of neural activity are perfectly balanced. The interplay between activating and inhibitory neurotransmitters ensures that the level of activity stays within the physiological range. Neuronal degeneration … Continue Reading Researchers begin to map neuroprotective pathway after epileptic seizure.
With Alzheimer’s disease medical professionals have to conduct costly brain imaging scans, and sometimes, invasive cerebral spinal fluid tests to rule out other diseases. Now, a new study from researchers … Continue Reading Human study identifies biomarker in blood for Alzheimer’s disease.
The standard model of natural selection predicts that once the age of reproduction ends, individuals die. That’s because selection early in life strongly favors variants that benefit reproductive success, even … Continue Reading Study identifies gene variants which protect older adults from neurodegeneration.
The blood-brain barrier represents a fundamental limitation in treating neurological disease because it prevents all neuropeptides from reaching the central nervous system (CNS). Currently, there is no efficient method to … Continue Reading New technique bypasses the blood-brain barrier to deliver neuroprotection.
Neural stem cells generate new neurons throughout life in the mammalian brain. Neural stem cells are self-renewing, multipotent cells that generate the main phenotype of the nervous system. Stem cells … Continue Reading Researchers identify neuroprotective mechanism against stem cell aging.
Today, more than 5.1 million Americans live with Alzheimer’s disease, a devastating type of dementia that plagues memory and thinking. That number is expected to triple in the coming decades. … Continue Reading Work begins on turning an ApoE4 Alzheimer’s brain into an ApoE2 Alzheimer’s brain.
Sigma receptors, particularly the sigma-1 receptor subtype, which are expressed in both neurons and glia of multiple regions within the central nervous system, are a unique class of intracellular proteins … Continue Reading Neuroprotective receptor found to have important role in support cells for the retina.
Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers discovered that increasing levels of a … Continue Reading Researchers identify previously unknown neuroprotective pathway in ALS.
About 15% of patients with Lyme disease develop peripheral and central nervous system involvement, often accompanied by debilitating and painful symptoms. Now, researchers from Tulane National Primate Research Center and Louisiana … Continue Reading Researchers map neuroinflammation and nervous system manifestations of Lyme disease.
Researchers have known that transplanted human umbilical cord cells (HUCBCs) can have a restorative effect on the brain and brain function following a stroke. However, just how the cells exert … Continue Reading Precision medicine used to counteract oxidative stress in stroke animal model.
A great year for healthinnovations with exciting discoveries, verifications, validations and breakthroughs. The big disease areas are still cancer, heart disease, diabetes and Alzheimer’s, however, it’s the methodology of detection, … Continue Reading The Top Ten Healthinnovations of 2014.
A new class of compounds has now been shown to protect brain cells from the type of damage caused by blast-mediated traumatic brain injury (TBI). Mice that were treated with … Continue Reading Compound protects brain cells after traumatic brain injury.
The same sex hormone that helps protect females from stroke may also reduce their risk of autism, scientists say. In the first look at a potential role of the female … Continue Reading Estrogen receptor expression may help explain why more males have autism.