Obesity and its associated illness type 2 diabetes (T2D) have reached epidemic proportions worldwide. Increased food intake and lack of exercise are two main contributing factors, with past research firmly … Continue Reading Specific microbiota identified which prevents obesity.
A decades-long raging epidemic, obesity has been shown to increase the risk of non-alcoholic fatty liver disease (NAFLD)in at least 30% of obese children, leading to liver failure requiring a … Continue Reading Alterations in infant microbiota linked to childhood obesity and liver disease.
Brown or good fat has long been investigated as a treatment for obesity and Type 2 diabetes due to the fact it burns energy faster than white fat, a type … Continue Reading Somatosensory neuron receptors used to form brown fat, have implications for diabetes and obesity.
Cell ablation is an important tool for selectively destroying one or multiple cells in a given organism to remove a disease such as cancer or to produce the desired response … Continue Reading Researchers successfully eliminate neurons outside the brain to trigger obesity.
Genetically-coded brain circuits can switch feeding and drinking behaviours on and off in mice.
Vital to our bodies, preproglucagon otherwise known as GCG peptides act in both the periphery and the CNS to change food intake, glucose homeostasis, and metabolic rate. Although the actions … Continue Reading Neurons successfully regulate appetite and glucose levels in mice.
It is known that around the body, fat deposits contain many mature fat cells and small numbers of stem cells. These stem cells can differentiate into more fat cells, however, … Continue Reading Hormone that controls maturation of fat stem cells identified.
When exposed to cold, clusters of cells within the body’s white fat become beige, a colour change which reflects the creation of more energy-producing mitochondria, cellular components that enable cells … Continue Reading Study shows that fat cells which amplify nerve signals in response to cold also affect blood sugar.
The decision to engage in food-seeking behaviour depends on homeostatic signals relating to energy balance and the presence of competing motivational drives, as well as learned brain cues signaling food … Continue Reading Neuroimaging shows the effect of hunger on the brain’s response to food cues.
Generally, researchers divide the human immune system into two parts. One part, called the innate immune system, allows for immediate and direct recognition of invading bacteria. It prompts immune cells … Continue Reading Study identifies previously unknown mechanism of the immune system.
About 8% of Americans have type 2 diabetes, and another 25% of the population is at risk because of obesity. Type 2 diabetes is a lifelong disease that represents an … Continue Reading Study identifies new pathway in insulin resistance.
The rapid rise in obesity and associated spread of type 2 diabetes represent an enormous challenge for society, with no efficient and safe medicines to prevent or stop this development … Continue Reading Astrocytes shown to control sugar in the brain, as well as neurons.
It is known that genetics plays a role in obesity, with genes directly causing obesity in disorders such as Bardet-Biedl syndrome and Prader-Willi syndrome. However, genes and behaviour may both … Continue Reading Human study shows ‘aggressive drunk’ gene may protect carriers from obesity and associated risks.
Understanding the integrative role of the central nervous system in the prevalence of obesity and obesity-related diseases is of great importance. It has been hypothesized that flexibility of food reward–related … Continue Reading Neuroimaging shows that response to food cues differ in severely obese women.
Obesity is a global health problem that poses a major risk factor for life-threatening diseases such as cardiovascular disease, cancer, and neurodegeneration. Recent studies have identified specific loci associated with … Continue Reading Study maps a molecular link between insulin-sensitivity and obesity.
Body mass index (BMI) is an important risk factor for breast cancer development and invasiveness. After menopause, women have an increased risk of developing breast cancer with increased BMI, while … Continue Reading New MRI technique links saturated fats to breast cancer in postmenopausal women.