Obesity is a significant risk factor for cardiovascular disease, diabetes, and cancer. Although obesity can stem from behavioural factors such as diet and physical inactivity, central nervous system changes can … Continue Reading Neuroimaging maps areas of the brain in obese children activated by food odours.
Obesity is associated with the risk of developing type-2 diabetes, nonalcoholic fatty liver disease, cardiovascular disease and cancer. However, it has been increasingly recognized that obesity is not a homogeneous … Continue Reading New test can warn patients years before onset of diabetes.
The intriguing relationship between metabolism and the immune system has been receiving increasing attention over the past few years. It is known that macrophages accumulate in adipose tissue during obesity. … Continue Reading Researchers identify immune cells that fight obesity in animal model.
All mammals, including humans, have two types of fat with completely opposite functions. These are white fat, which stores energy and is linked with diabetes and obesity; and brown fat, … Continue Reading Researchers identify epigenetic switch which generates calorie-burning brown fat.
A primary function of cytokines is to initiate immune responses; however, it has become increasingly apparent that they play major roles in the regulation of energy homeostasis, implicating them in … Continue Reading Sensor protein shown to have dual role in immune-system and metabolism.
White adipose tissue, or fat tissue, serves as a storage depot for energy-rich triglycerides. In times of need this lipid storage can be released as part of an adaptive response … Continue Reading Researchers identify previously unknown neural mechanism responsible for fat breakdown.
Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health, leading to reduced life expectancy and … Continue Reading Researchers link obesity to a faulty immune system in animal model.
It’s been known that in the presence of obesity, the endoplasmic reticulum (ER) dysfunction is unable to perform one of its key functions: initiating a cascade of intracellular events called … Continue Reading New obesity-related mechanism identified in the development of Type 2 diabetes.
It is well-known that insulin resistance is common in people who are obese, pre-diabetic or have Type 2 diabetes. The fact that obesity increases the risk of cardiovascular disease and … Continue Reading Researchers image the effect of insulin resistance in the brain, link to Alzheimer’s disease.
Triglycerides, like cholesterol, are lipids. They come from fats carried by food or produced by the human body. Depending on the cause, the accumulation of triglycerides in blood is associated … Continue Reading Researchers use precision medicine to reduce the amount of fat in patient’s blood.
While all red and white blood cells derive from stem cells in the bone marrow, the scientific community has been divided as to whether bone marrow cells are also able … Continue Reading Long-term study uncovers previously unknown mechanism of the formation of fat tissue in humans.
Practically everyone gets fatter as they get older, however, according to a new study from researchers at Duke University some people can blame their genes for the extra padding. The … Continue Reading Researchers identify gene responsible for obesity and diabetes in old age.
Metabolism experts are increasingly convinced that obesity and many of the pathogenic changes it entails, such as Metabolic Syndrome and type 2 diabetes, are a result of chronic inflammatory processes … Continue Reading Researchers identify enzyme in animal model responsible for metabolism disorders due to obesity.
Obesity is a serious health problem affecting approximately one-third of the adult population in the United States. Obese individuals have an increased risk of diabetes and cardiovascular disease, including hypertension. … Continue Reading Researchers identify the enzyme responsible for obesity-related high blood pressure.
Researchers at the University of North Carolina and the National Institutes of Health (NIH) have perfected a noninvasive ‘chemogenetic’ technique that allows them to switch off a specific behaviour in … Continue Reading New chemogenetic tool is the first to target different kinds of receptors on a neuron sequentially.
The micro RNA miR-22 has long been known for its ability to suppress cancer. However, questions remain about how it achieves this feat. For example, which molecules are regulating miR-22, … Continue Reading Researchers being to map the epigenetic pathway of miR-22 cancer suppression.