It’s long been known that excess iron is found in the brains of patients with Parkinson’s disease (PD), an incurable neurodegenerative condition that affects motor function. However, the mechanism by … Continue Reading Researchers identify the neurogenetic basis of excess iron in Parkinson’s disease.
Sigma receptors, particularly the sigma-1 receptor subtype, which are expressed in both neurons and glia of multiple regions within the central nervous system, are a unique class of intracellular proteins … Continue Reading Neuroprotective receptor found to have important role in support cells for the retina.
When cells are normal and unstressed, the molecule keeps transcription moving so that genes are ‘expressed’ and RNA is jotted down more quickly. When cells are stressed and transcription runs … Continue Reading Researchers identify key molecule which halts transcription of cell’s genetic code.
Scientists from the Institut Pasteur, CNRS, Institut Gustave Roussy and CEA, have succeeded in restoring normal activity in cells isolated from patients with the premature aging disease Cockayne syndrome. They … Continue Reading Researchers identify and correct premature aging in diseased cells.
Oxidative stress has become a major topic; not only is it implicated in many diseases, it may even be one of their causes. Other environmental influences besides UV radiation can … Continue Reading Researchers use precision medicine to prove the effectiveness of Vitamin E as an antioxidant.
A protein that helps embryonic stem cells retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that … Continue Reading Researchers identify protein responsible for DNA repair at a stem cell level.
Stating that sleep is an essential biological process seems as obvious as saying that the sun rises every morning. Yet, researchers’ understanding of the molecular mechanisms underlying the effects of … Continue Reading Lipidomics study identifies common biomarkers of sleep debt in humans and rats.
Researchers have known that transplanted human umbilical cord cells (HUCBCs) can have a restorative effect on the brain and brain function following a stroke. However, just how the cells exert … Continue Reading Precision medicine used to counteract oxidative stress in stroke animal model.
Injectable nanoparticles that could protect an injured person from further damage due to oxidative stress have proven to be astoundingly effective in tests to study their mechanism. Scientists at Rice … Continue Reading Nano-antioxidants shown to have ‘enormous’ capability to quench superoxides after traumatic injury.
Researchers have discovered a mechanism linked to the brain damage often suffered by stroke victims, and are now searching for drugs to block it. Strokes happen when the blood supply … Continue Reading Researchers identify the mechanism of stroke damage.
While developing a new cancer drug, researchers at The Wistar Institute discovered that mice lacking a specific protein live longer lives with fewer age-related illnesses. The mice, which lack the … Continue Reading ‘Rewired’ mice show signs of longer lives with fewer age-related illnesses.