An intricate sensory network intertwined across our bodies, the nervous system requires a specialized network of blood vessels for its development and survival. However, it is still unclear as to … Continue Reading Study shows that neurons modulate the growth of blood vessels.
Pain hypersensitivity can spread to unaffected body regions immediately surrounding the initial insult. Sometimes it can even spread to the opposite site of the body or to large body areas … Continue Reading Pain-initiating function of glial cells identified for the first time.
Stem cells are non-specialized cells found in different organs, which have the capacity to generate specialized cells in the body. In the adult brain, neural stem cells give rise to … Continue Reading Study shows cerebrospinal fluid signals control the behaviour of stem cells in the brain.
In Kennedy’s disease, the muscle cells and motor neurons, which are also linked to muscle function, are damaged as a result of the accumulation of androgen receptor fibers, a process … Continue Reading Identification of a neuroprotector linked to a degenerative neuromuscular disease.
Delayed deterioration of neurological function after ischemia stroke is a well-documented clinical problem. However, minimal studies exist pertaining to spinal cord blood flow and blood-spinal cord barrier (BSCB) integrity with … Continue Reading Study maps how a stroke damages the blood-spinal cord barrier.
Spinal muscular atrophy is a debilitating disease that causes weakness and wasting of the muscles. The disease ranges in severity with patients experiencing different symptoms, from the inability to sit … Continue Reading Molecular mechanism underlying neurodegeneration in spinal muscular atrophy identified.
Neuropathic pain is deﬁned as pain initiated or caused by a primary lesion or dysfunction in the nervous system. Chronic neuropathic leg pain is the most common form of neuropathic … Continue Reading Neuroimaging shows that spinal cord stimulation reduces emotional aspect of chronic pain.
During embryonic development, billions of neurons nimbly reposition themselves within the brain and spinal cord, and connect branches to form the neural circuits that ultimately control our movements, perception, and … Continue Reading Previously unknown molecule critical for neurodevelopment identified.
Mobility after paraplegia due to spinal cord injury (SCI) is primarily achieved by substituting the lost function with a wheelchair. However, the sedentary lifestyle associated with excessive wheelchair reliance can … Continue Reading Brain-computer interface enables paralyzed man to walk in world’s first.
When a person walks around the block, their body is mostly on autopilot; they don’t have to consciously think about alternating each step or which muscles it takes to lift … Continue Reading Researchers visualise motor neurons in real-time on a genetic sub-type level.
Five men with complete motor paralysis were able to voluntarily generate step-like movements thanks to a new strategy that non-invasively delivers electrical stimulation to their spinal cords, according to a … Continue Reading Paralyzed men move legs with new non-invasive spinal cord stimulation.
Chronic spinal cord injury (SCI) is a formidable hurdle that prevents a large number of injured axons from crossing the lesion, particularly the corticospinal tract (CST). Patients inflicted with SCI … Continue Reading Researchers identify precision medicine to regenerate corticospinal tract axons.
Resarchers have successfully transplanted olfactory cells to treat spinal cord injury in human trials.
Researchers from the Wenzhou Medical University state they have successfully repaired spinal cord injuries using the patients’ olfactory mucosa in human trials. Three years after they treated patients with spinal … Continue Reading Resarchers have successfully transplanted olfactory cells to treat spinal cord injury in human trials.
A chemical in the brain typically associated with cognition, movement and reward-motivation behaviour, among others, may also play a role in promoting chronic pain, according to new research from researchers … Continue Reading Researchers map dopamine based chronic-pain pathway in the spinal cord and brain.
Researchers successfully implant and control light-sensitive opioid receptors in mice via optogenetics.
Despite the abuse potential of opioid drugs, they have long been the best option for patients suffering from severe pain. The drugs interact with receptors on brain cells to tamp … Continue Reading Researchers successfully implant and control light-sensitive opioid receptors in mice via optogenetics.
In a new study from Saint Louis University, researchers discovered that drugs targeting the A3 adenosine receptor can turn off pain signals in the spinal cord to provide relief from … Continue Reading Researchers use A3 adenosine receptors to activate ‘off signals’ for chronic pain.