Stem cell treatments for neurodegenerative diseases are expected to reach clinical trials soon. One major task en route to the clinic is to generate standardized good manufacturing practice (GMP)-grade human-pluripotent … Continue Reading Breakthrough in the production of dopamine neurons for Parkinson’s disease.
It is known that skeletal muscle regeneration is impaired in age-related diseases such as sarcopenia, which is marked by reduced muscle regenerative capacity with aging, due in part to a … Continue Reading Study identifies gene responsible for regeneration of injured muscle by adult stem cells.
Obesity is a metabolic disorder resulting from behavioral and heritable causes. Children of obese fathers are at higher risk of developing metabolic disease later in life, independent of the body … Continue Reading Study maps epigenetics of father’s weight passed on by his sperm.
Mammalian skeletal muscles can regenerate following injury and this response is mediated by a specific type of stem cell, the satellite cell. Significant evidence suggests that while stem cells represent … Continue Reading Previously unknown mechanism in skeletal muscle regeneration identified.
In the field of iPS cell-based regenerative medicine, advanced research with clinical applications for many organs and tissues, such as the retina, has steadily progressed. However, growing a kidney from … Continue Reading Human stem cell-derived kidneys connect to blood vessels when transplanted into mice.
In human blood formation, everything begins with the stem cell, which is the executive decision-maker quickly driving the process that replenishes blood at a daily rate that exceeds 300 billion … Continue Reading Researchers redefine how blood is made.
Aging is a major risk factor for many human diseases, and in vitro generation of human neurons is an attractive approach for modeling aging-related brain disorders. While aggressive familial early … Continue Reading New technique enables researchers to grow old human brain cells for the first time.
A research group from Helmholtz Zentrum München has developed an assay whereby mini-breasts in-a-dish can be grown, with cultured human breast epithelial cells rebuilt into the three-dimensional tissue architecture of the … Continue Reading Researchers grow mini breast-in-a-dish, provide breakthrough in breast cancer proliferation.
A research group from the Cluster of Excellence at the TU Dresden (CRTD) demonstrated for the first time the in vitro growth of a piece of spinal cord in three … Continue Reading Spatially, anatomically correct spinal cord grown in the lab for the first time.