Category Archives: TP53

Researchers begin to map inherited gene mutations in colorectal cancer.


In a group of patients diagnosed with colorectal cancer at 40 or younger, 1.3 percent of the patients carried germline TP53 gene mutations, although none of the patients met the clinical criteria for an inherited cancer syndrome associated with higher lifetime risks of multiple cancers, according to a study published by JAMA Oncology. Li-Fraumeni syndrome is an inherited cancer syndrome

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