All mammals, including humans, have two types of fat with completely opposite functions. These are white fat, which stores energy and is linked with diabetes and obesity; and brown fat, … Continue Reading Researchers identify epigenetic switch which generates calorie-burning brown fat.
A primary function of cytokines is to initiate immune responses; however, it has become increasingly apparent that they play major roles in the regulation of energy homeostasis, implicating them in … Continue Reading Sensor protein shown to have dual role in immune-system and metabolism.
Ten million Canadians are living with diabetes or pre-diabetes. The Canadian Diabetes Association reports that more than 20 Canadians are newly diagnosed with the disease every hour of every day. … Continue Reading New mitochondria-based insulin amplifier pathway identified in T2 diabetes.
High blood sugar is a defining characteristic of Type 2 diabetes and the cause of many of the condition’s complications, including kidney failure, heart disease, and blindness. Most diabetes medications … Continue Reading Researchers block mitochondrial glucose production to treat type 2 diabetes in preclinical trials.
It’s been known that in the presence of obesity, the endoplasmic reticulum (ER) dysfunction is unable to perform one of its key functions: initiating a cascade of intracellular events called … Continue Reading New obesity-related mechanism identified in the development of Type 2 diabetes.
It is well-known that insulin resistance is common in people who are obese, pre-diabetic or have Type 2 diabetes. The fact that obesity increases the risk of cardiovascular disease and … Continue Reading Researchers image the effect of insulin resistance in the brain, link to Alzheimer’s disease.
Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been … Continue Reading New diagnostic identifies mitochondria dysfunction in Type 2 diabetes.
Approximately 28 million Americans live with Type 2 diabetes, a condition characterized by high blood sugar levels. The immune system plays a part in type 2 diabetes. Researchers have linked … Continue Reading Decades old mystery solved as researchers map the effect of T2 diabetes on the lymphatic vessels.
Practically everyone gets fatter as they get older, however, according to a new study from researchers at Duke University some people can blame their genes for the extra padding. The … Continue Reading Researchers identify gene responsible for obesity and diabetes in old age.
A new neuroimaging study has shown that in just two years people with type 2 diabetes experienced negative changes in their ability to regulate blood flow in the brain This … Continue Reading Long-term human study shows detrimental effect diabetes has on brain plasticity.
Metabolism experts are increasingly convinced that obesity and many of the pathogenic changes it entails, such as Metabolic Syndrome and type 2 diabetes, are a result of chronic inflammatory processes … Continue Reading Researchers identify enzyme in animal model responsible for metabolism disorders due to obesity.
Scientists at the University of British Columbia and Janssen LLC have shown for the first time that Type 2 diabetes can be effectively treated with a combination of specially-cultured stem … Continue Reading Differentiation therapy shows promise for reversing type 2 diabetes in animal model.