A germline mutation is any detectable and heritable variation in the lineage of germ cells, any biological cell that gives rise to the gametes of an organism in sexual reproduction. … Continue Reading Study provides most detailed analysis yet of germline mutations involved in childhood cancers.
Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent … Continue Reading Researchers identify new gene responsible for liver disease.
Even with modern whole-genome sequencing techniques, it has proven difficult to identify genetic factors affecting risk for depression, according to an opensource literature review in the Harvard Review of Psychiatry. … Continue Reading Harvard-led literature review on genetics in depression, what’s known, what’s next.
DNA sequences were once thought to be identical from cell to cell, but it’s increasingly understood that mutations can arise during brain development that affect only certain groups of brain … Continue Reading New single-cell sequencing technique can track subtle neurogenetic mutations spatially.
UT Southwestern Medical Center researchers have demonstrated that whole-genome sequencing can be used to identify patients’ risk for hereditary cancer, which can potentially lead to improvements in cancer prevention, diagnosis, … Continue Reading Researchers confirm whole-genome sequencing can identify cancer-related mutations and risk.