Flagella and cilia are slender organellar protrusions of the eukaryotic cell membrane with sensory and motor function. Flagella and cilia are similar in that they share a microtubule-based cytoskeleton called … Continue Reading Researchers identify lipid responsible for keeping brain fluid moving.
Mammalian embryos start out as a small group of identical cells. Then at an early stage, some of these cells take up an internal position within the embryo. These internal … Continue Reading Researchers visualise mammalian embryo formation for the first time.
Scientists from the CNRS, INSERM and Université de Limoges have demonstrated that the production of type E immunoglobulins (IgE)2 by B lymphocytes induces a loss in their mobility and the … Continue Reading Researchers map programmed cell death in immune cells to prevent allergy.
A new study from the Albert Einstein College of Medicine and the University of Pittsburgh details how cells with low levels of the profilin 1 protein in breast tumours increase their … Continue Reading Researchers identify protein crucial for breast cancer metastasis ‘scaffolding’.
Defective cilia can lead to a host of diseases and conditions in the human body, from rare, inherited bone malformations to blindness, male infertility, kidney disease and obesity. It is … Continue Reading Researchers video and measure tubulin transport in cilia for the first time.
Researchers at University of California, San Diego Skaggs School and the University of Southern California report the first crystal structure of the cellular receptor CXCR4 bound to an immune signaling … Continue Reading Researchers capture the 3d structure of a chemokine and its receptor for the first time.
Cells have finger-like projections that they use to feel their surroundings. They can detect the chemical environment and they can ‘feel’ their physical surroundings using ultrasensitive sensors. New research from … Continue Reading New mechanism of cell movement identified and imaged for the first time.
For decades, researchers have used petri dishes to study cell movement. These classic tissue culture tools, however, only permit two-dimensional movement, very different from the three-dimensional movements that cells make … Continue Reading Penn-NIH team discover new type of cell movement.